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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Beclin-1

SKU : BHE13801627

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1025m
Alternative Names	Coiled-coil myosin-like BCL2-interacting protein
Categories	Elisa
Function	Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense.
Specificity	Natural and recombinant Mouse Beclin-1
Subcellular Location	Cytoplasm Golgi apparatus trans-Golgi network membrane Peripheral membrane protein Interaction with ATG14 promotes translocation to autophagosomes (By similarity). Expressed in dendrites and cell bodies of cerebellar Purkinje cells.
Detection Range	0.156-10ng/mL
Entryname	BECN1_MOUSE
Method Type	Sandwich
Platform	PF04111
Protein Name	Beclin-1
Sensitivity	0.078ng/mL
Sequence	50: MEGSKASSST ; MQVSFVCQRC ; SQPLKLDTSF ; KILDRVTIQE ; LTAPLLTTAQ ; 100: AKPGETQEEE ; ANSGEEPFIE ; TRQDGVSRRF ; IPPARMMSTE ; SANSFTLIGE ; 150: ASDGGTMENL ; SRRLKVTGDL ; FDIMSGQTDV ; DHPLCEECTD ; TLLDQLDTQL ; 200: NVTENECQNY ; KRCLEILEQM ; NEDDSEQLQR ; ELKELALEEE ; RLIQELEDVE ; 250: KNRKVVAENL ; EKVQAEAERL ; DQEEAQYQRE ; YSEFKRQQLE ; LDDELKSVEN ; 300: QVRYAQIQLD ; KLKKTNVFNA ; TFHIWHSGQF ; GTINNFRLGR ; LPSVPVEWNE ; 350: INAAWGQTVL ; LLHALANKMG ; LKFQRYRLVP ; YGNHSYLESL ; TDKSKELPLY ; 400: CSGGLRFFWD ; NKFDHAMVAF ; LDCVQQFKEE ; VEKGETRFCL ; PYRMDVEKGK ; 448: IEDTGGSGGS ; YSIKTQFNSE ; EQWTKALKFM ; LTNLKWGLAW ; VSSQFYNK
Sequence Length	448
String	O88597
Sub Unit	Interacts with BCL2 and BCL2L1 (By similarity). Interacts with GOPC and GRID2. Interacts with AMBRA1. Forms a complex with PIK3C3 and PIK3R4 and either UVRAG and Rubicon, or with ATG14. UVRAG and ATG14 form mutually exclusive complexes through direct competition for BECN1-binding. The complex containing ATG14 upregulates autophagy, while the one containing Rubicon downregulates autophagy. Interacts with VMP1 (By similarity). Interacts with PIK3CB.

Uniprot	O88597
Gene Name	Becn1
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:56208
Unigene	Mm.178947

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SKU	Supplier No.	Size	Your price	Quantity
BHE13801627	E1025m	96T	$776		Add to Cart

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