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ELISA Kit for Human Zinc finger homeobox protein 3

SKU : BHE13811628

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1065h
Alternative Names	AT motif-binding factor 1 ; AT-binding transcription factor 1 ; Alpha-fetoprotein enhancer-binding protein ; Zinc finger homeodomain protein 3 ; ZFH-3 ; ATBF1
Categories	Elisa
Function	Transcriptional repressor. It inhibits the enhancer element of the AFP gene by binding to its AT-rich core sequence. Regulator of myoblasts differentiation through the binding to the AT-rich sequence of MYF6 promoter and promoter repression. Down-regulates the MUC5AC promoter in gastric cancer.
Specificity	Natural and recombinant Human Zinc finger homeobox protein 3
Subcellular Location	Nucleus
Detection Range	78-5000pg/mL
Entryname	ZFHX3_HUMAN
Method Type	Sandwich
Platform	PF00046
Protein Name	Zinc finger homeobox protein 3
Sensitivity	32pg/mL
Sequence	50: MEGCDSPVVS ; GKDNGCGIPQ ; HQQWTELNST ; HLPDKPSSME ; QSTGESHGPL ; 100: DSLRAPFNER ; LAESTASAGP ; PSEPASKEVT ; CNECSASFAS ; LQTYMEHHCP ; 150: SARPPPPLRE ; ESASDTGEEG ; DEESDVENLA ; GEIVYQPDGS ; AYIVESLSQL ; 200: TQGGGACGSG ; SGSGPLPSLF ; LNSLPGAGGK ; QGDPSCAAPV ; YPQIINTFHI ; 250: ASSFGKWFEG ; PDQAFPNTSA ; LAGLSPVLHS ; FRVFDVRHKS ; NKDYLNSDGS ; 300: AKSSCVSKDV ; PNNVDLSKFD ; GFVLYGKRKP ; ILMCFLCKLS ; FGYVRSFVTH ; 350: AVHDHRMTLS ; EDERKILSNK ; NISAIIQGIG ; KDKEPLVSFL ; EPKNKNFQHP ; 400: LVSTANLIGP ; GHSFYGKFSG ; IRMEGEEALP ; AGSAAGPEQP ; QAGLLTPSTL ; 450: LNLGGLTSSV ; LKTPITSVPL ; GPLASSPTKS ; SEGKDSGAAE ; GEKQEVGDGD ; 500: CFSEKVEPAE ; EEAEEEEEEE ; EAEEEEEEEE ; EEEEEEEDEG ; CKGLFPSELD ; 550: EELEDRPHEE ; PGAAAGSSSK ; KDLALSNQSI ; SNSPLMPNVL ; QTLSRGTAST ; 600: SSNSASSFVV ; FDGANRRNRL ; SFNSEGVRAN ; VAEGGRRLDF ; ADESANKDNA ; 650: TAPEPNESTE ; GDDGGFVPHH ; QHAGSLCELG ; VGECPSGSGV ; ECPKCDTVLG ; 700: SSRSLGGHMT ; MMHSRNSCKT ; LKCPKCNWHY ; KYQQTLEAHM ; KEKHPEPGGS ; 750: CVYCKSGQPH ; PRLARGESYT ; CGYKPFRCEV ; CNYSTTTKGN ; LSIHMQSDKH ; 800: LNNMQNLQNG ; GGEQVFSHTA ; GAAAAAVAAA ; AAAANISSSC ; GAPSPTKPKT ; 850: KPTWRCEVCD ; YETNVARNLR ; IHMTSEKHMH ; NMMLLQQNMT ; QIQHNRHLGL ; 900: GSLPSPAEAE ; LYQYYLAQNM ; NLPNLKMDSA ; ASDAQFMMSG ; FQLDPAGPMA ; 950: AMTPALVGGE ; IPLDMRLGGG ; QLVSEELMNL ; GESFIQTNDP ; SLKLFQCAVC ; 1000: NKFTTDNLDM ; LGLHMNVERS ; LSEDEWKAVM ; GDSYQCKLCR ; YNTQLKANFQ ; 1050: LHCKTDKHVQ ; KYQLVAHIKE ; GGKANEWRLK ; CVAIGNPVHL ; KCNACDYYTN ; 1100: SLEKLRLHTV ; NSRHEASLKL ; YKHLQQHESG ; VEGESCYYHC ; VLCNYSTKAK ; 1150: LNLIQHVRSM ; KHQRSESLRK ; LQRLQKGLPE ; EDEDLGQIFT ; IRRCPSTDPE ; 1200: EAIEDVEGPS ; ETAADPEELA ; KDQEGGASSS ; QAEKELTDSP ; ATSKRISFPG ; 1250: SSESPLSSKR ; PKTAEEIKPE ; QMYQCPYCKY ; SNADVNRLRV ; HAMTQHSVQP ; 1300: MLRCPLCQDM ; LNNKIHLQLH ; LTHLHSVAPD ; CVEKLIMTVT ; TPEMVMPSSM ; 1350: FLPAAVPDRD ; GNSNLEEAGK ; QPETSEDLGK ; NILPSASTEQ ; SGDLKPSPAD ; 1400: PGSVREDSGF ; ICWKKGCNQV ; FKTSAALQTH ; FNEVHAKRPQ ; LPVSDRHVYK ; 1450: YRCNQCSLAF ; KTIEKLQLHS ; QYHVIRAATM ; CCLCQRSFRT ; FQALKKHLET ; 1500: SHLELSEADI ; QQLYGGLLAN ; GDLLAMGDPT ; LAEDHTIIVE ; EDKEEESDLE ; 1550: DKQSPTGSDS ; GSVQEDSGSE ; PKRALPFRKG ; PNFTMEKFLD ; PSRPYKCTVC ; 1600: KESFTQKNIL ; LVHYNSVSHL ; HKLKRALQES ; ATGQPEPTSS ; PDNKPFKCNT ; 1650: CNVAYSQSST ; LEIHMRSVLH ; QTKARAAKLE ; AASGSSNGTG ; NSSSISLSSS ; 1700: TPSPVSTSGS ; NTFTTSNPSS ; AGIAPSSNLL ; SQVPTESVGM ; PPLGNPIGAN ; 1750: IASPSEPKEA ; NRKKLADMIA ; SRQQQQQQQQ ; QQQQQQQQQQ ; QAQTLAQAQA ; 1800: QVQAHLQQEL ; QQQAALIQSQ ; LFNPTLLPHF ; PMTTETLLQL ; QQQQHLLFPF ; 1850: YIPSAEFQLN ; PEVSLPVTSG ; ALTLTGTGPG ; LLEDLKAQVQ ; VPQQSHQQIL ; 1900: PQQQQNQLSI ; AQSHSALLQP ; SQHPEKKNKL ; VIKEKEKESQ ; RERDSAEGGE ; 1950: GNTGPKETLP ; DALKAKEKKE ; LAPGGGSEPS ; MLPPRIASDA ; RGNATKALLE ; 2000: NFGFELVIQY ; NENKQKVQKK ; NGKTDQGENL ; EKLECDSCGK ; LFSNILILKS ; 2050: HQEHVHQNYF ; PFKQLERFAK ; QYRDHYDKLY ; PLRPQTPEPP ; PPPPPPPPPP ; 2100: LPAAPPQPAS ; TPAIPASAPP ; ITSPTIAPAQ ; PSVPLTQLSM ; PMELPIFSPL ; 2150: MMQTMPLQTL ; PAQLPPQLGP ; VEPLPADLAQ ; LYQHQLNPTL ; LQQQNKRPRT ; 2200: RITDDQLRVL ; RQYFDINNSP ; SEEQIKEMAD ; KSGLPQKVIK ; HWFRNTLFKE ; 2250: RQRNKDSPYN ; FSNPPITSLE ; ELKIDSRPPS ; PEPPKQEYWG ; SKRSSRTRFT ; 2300: DYQLRVLQDF ; FDANAYPKDD ; EFEQLSNLLN ; LPTRVIVVWF ; QNARQKARKN ; 2350: YENQGEGKDG ; ERRELTNDRY ; IRTSNLNYQC ; KKCSLVFQRI ; FDLIKHQKKL ; 2400: CYKDEDEEGQ ; DDSQNEDSMD ; AMEILTPTSS ; SCSTPMPSQA ; YSAPAPSANN ; 2450: TASSAFLQLT ; AEAEELATFN ; SKTEAGDEKP ; KLAEAPSAQP ; NQTQEKQGQP ; 2500: KPELQQQEQP ; EQKTNTPQQK ; LPQLVSLPSL ; PQPPPQAPPP ; QCPLPQSSPS ; 2550: PSQLSHLPLK ; PLHTSTPQQL ; ANLPPQLIPY ; QCDQCKLAFP ; SFEHWQEHQQ ; 2600: LHFLSAQNQF ; IHPQFLDRSL ; DMPFMLFDPS ; NPLLASQLLS ; GAIPQIPASS ; 2650: ATSPSTPTST ; MNTLKRKLEE ; KASASPGEND ; SGTGGEEPQR ; DKRLRTTITP ; 2700: EQLEILYQKY ; LLDSNPTRKM ; LDHIAHEVGL ; KKRVVQVWFQ ; NTRARERKGQ ; 2750: FRAVGPAQAH ; RRCPFCRALF ; KAKTALEAHI ; RSRHWHEAKR ; AGYNLTLSAM ; 2800: LLDCDGGLQM ; KGDIFDGTSF ; SHLPPSSSDG ; QGVPLSPVSK ; TMELSPRTLL ; 2850: SPSSIKVEGI ; EDFESPSMSS ; VNLNFDQTKL ; DNDDCSSVNT ; AITDTTTGDE ; 2900: GNADNDSATG ; IATETKSSSA ; PNEGLTKAAM ; MAMSEYEDRL ; SSGLVSPAPS ; 2950: FYSKEYDNEG ; TVDYSETSSL ; ADPCSPSPGA ; SGSAGKSGDS ; GDRPGQKRFR ; 3000: TQMTNLQLKV ; LKSCFNDYRT ; PTMLECEVLG ; NDIGLPKRVV ; QVWFQNARAK ; 3050: EKKSKLSMAK ; HFGINQTSYE ; GPKTECTLCG ; IKYSARLSVR ; DHIFSQQHIS ; 3100: KVKDTIGSQL ; DKEKEYFDPA ; TVRQLMAQQE ; LDRIKKANEV ; LGLAAQQQGM ; 3150: FDNTPLQALN ; LPTAYPALQG ; IPPVLLPGLN ; SPSLPGFTPS ; NTALTSPKPN ; 3200: LMGLPSTTVP ; SPGLPTSGLP ; NKPSSASLSS ; PTPAQATMAM ; GPQQPPQQQQ ; 3250: QQQQPQVQQP ; PPPPAAQPPP ; TPQLPLQQQQ ; QRKDKDSEKV ; KEKEKAHKGK ; 3300: GEPLPVPKKE ; KGEAPTATAA ; TISAPLPTME ; YAVDPAQLQA ; LQAALTSDPT ; 3350: ALLTSQFLPY ; FVPGFSPYYA ; PQIPGALQSG ; YLQPMYGMEG ; LFPYSPALSQ ; 3400: ALMGLSPGSL ; LQQYQQYQQS ; LQEAIQQQQQ ; RQLQQQQQQK ; VQQQQPKASQ ; 3450: TPVPPGAPSP ; DKDPAKESPK ; PEEQKNTPRE ; VSPLLPKLPE ; EPEAESKSAD ; 3500: SLYDPFIVPK ; VQYKLVCRKC ; QAGFSDEEAA ; RSHLKSLCFF ; GQSVVNLQEM ; 3550: VLHVPTGGGG ; GGSGGGGGGG ; GGGGGGGSYH ; CLACESALCG ; EEALSQHLES ; 3600: ALHKHRTITR ; AARNAKEHPS ; LLPHSACFPD ; PSTASTSQSA ; AHSNDSPPPP ; 3650: SAAAPSSASP ; HASRKSWPQV ; VSRASAAKPP ; SFPPLSSSST ; VTSSSCSTSG ; 3700: VQPSMPTDDY ; SEESDTDLSQ ; KSDGPASPVE ; GPKDPSCPKD ; SGLTSVGTDT ; 3703: FRL
Sequence Length	3703
String	Q15911
Sub Unit	Interacts with FNBP3 (By similarity). Interacts with PIAS3.

Uniprot	Q15911
Gene Name	ZFHX3
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:463
Unigene	Hs.598297

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