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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Zinc finger E-box-binding homeobox 1

SKU : BHE13810967

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E14970h
Alternative Names	NIL-2-A zinc finger protein ; Negative regulator of IL2 ; Transcription factor 8 ; TCF-8 ; AREB6 ; TCF8
Categories	Elisa
Function	Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.
Specificity	Natural and recombinant Human Zinc finger E-box-binding homeobox 1
Subcellular Location	Nucleus
Detection Range	0.312-20ng/mL
Entryname	ZEB1_HUMAN
Method Type	Sandwich
Platform	PF00046
Protein Name	Zinc finger E-box-binding homeobox 1
Sensitivity	0.23ng/ml
Sequence	50: MADGPRCKRR ; KQANPRRNNV ; TNYNTVVETN ; SDSDDEDKLH ; IVEEESVTDA ; 100: ADCEGVPEDD ; LPTDQTVLPG ; RSSEREGNAK ; NCWEDDRKEG ; QEILGPEAQA ; 150: DEAGCTVKDD ; ECESDAENEQ ; NHDPNVEEFL ; QQQDTAVIFP ; EAPEEDQRQG ; 200: TPEASGHDEN ; GTPDAFSQLL ; TCPYCDRGYK ; RFTSLKEHIK ; YRHEKNEDNF ; 250: SCSLCSYTFA ; YRTQLERHMT ; SHKSGRDQRH ; VTQSGCNRKF ; KCTECGKAFK ; 300: YKHHLKEHLR ; IHSGEKPYEC ; PNCKKRFSHS ; GSYSSHISSK ; KCISLIPVNG ; 350: RPRTGLKTSQ ; CSSPSLSASP ; GSPTRPQIRQ ; KIENKPLQEQ ; LSVNQIKTEP ; 400: VDYEFKPIVV ; ASGINCSTPL ; QNGVFTGGGP ; LQATSSPQGM ; VQAVVLPTVG ; 450: LVSPISINLS ; DIQNVLKVAV ; DGNVIRQVLE ; NNQANLASKE ; QETINASPIQ ; 500: QGGHSVISAI ; SLPLVDQDGT ; TKIIINYSLE ; QPSQLQVVPQ ; NLKKENPVAT ; 550: NSCKSEKLPE ; DLTVKSEKDK ; SFEGGVNDST ; CLLCDDCPGD ; INALPELKHY ; 600: DLKQPTQPPP ; LPAAEAEKPE ; SSVSSATGDG ; NLSPSQPPLK ; NLLSLLKAYY ; 650: ALNAQPSAEE ; LSKIADSVNL ; PLDVVKKWFE ; KMQAGQISVQ ; SSEPSSPEPG ; 700: KVNIPAKNND ; QPQSANANEP ; QDSTVNLQSP ; LKMTNSPVLP ; VGSTTNGSRS ; 750: STPSPSPLNL ; SSSRNTQGYL ; YTAEGAQEEP ; QVEPLDLSLP ; KQQGELLERS ; 800: TITSVYQNSV ; YSVQEEPLNL ; SCAKKEPQKD ; SCVTDSEPVV ; NVIPPSANPI ; 850: NIAIPTVTAQ ; LPTIVAIADQ ; NSVPCLRALA ; ANKQTILIPQ ; VAYTYSTTVS ; 900: PAVQEPPLKV ; IQPNGNQDER ; QDTSSEGVSN ; VEDQNDSDST ; PPKKKMRKTE ; 950: NGMYACDLCD ; KIFQKSSSLL ; RHKYEHTGKR ; PHECGICKKA ; FKHKHHLIEH ; 1000: MRLHSGEKPY ; QCDKCGKRFS ; HSGSYSQHMN ; HRYSYCKREA ; EERDSTEQEE ; 1050: AGPEILSNEH ; VGARASPSQG ; DSDERESLTR ; EEDEDSEKEE ; EEEDKEMEEL ; 1100: QEEKECEKPQ ; GDEEEEEEEE ; EVEEEEVEEA ; ENEGEEAKTE ; GLMKDDRAES ; 1124: QASSLGQKVG ; ESSEQVSEEK ; TNEA
Sequence Length	1124
String	P37275
Sub Unit	Interacts (via N-terminus) with SMARCA4/BRG1.

Uniprot	P37275
Gene Name	ZEB1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:6935
Unigene	Hs.124503

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810967	E14970h	96T	$736		Add to Cart

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