Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform 2 and isoform 3 may have an inhibitory role in angiogenesis.
Specificity
Natural and recombinant Human Vascular endothelial growth factor receptor 1