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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Vascular endothelial growth factor A

SKU : BHE13811943

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0143h
Alternative Names	Vascular permeability factor ; VPF ; VEGF
Categories	Elisa
Function	Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.
Specificity	Natural and recombinant Human Vascular endothelial growth factor A
Subcellular Location	Secreted VEGF121 is acidic and freely secreted. VEGF165 is more basic, has heparin-binding properties and, although a signicant proportion remains cell-associated, most is freely secreted. VEGF189 is very basic, it is cell-associated after secretion and is bound avidly by heparin and the extracellular matrix, although it may be released as a soluble form by heparin, heparinase or plasmin.
Detection Range	78-5000pg/mL
Entryname	VEGFA_HUMAN
Method Type	Sandwich
Platform	PF00341
Protein Name	Vascular endothelial growth factor A
Sensitivity	43pg/mL
Sequence	50: MNFLLSWVHW ; SLALLLYLHH ; AKWSQAAPMA ; EGGGQNHHEV ; VKFMDVYQRS ; 100: YCHPIETLVD ; IFQEYPDEIE ; YIFKPSCVPL ; MRCGGCCNDE ; GLECVPTEES ; 150: NITMQIMRIK ; PHQGQHIGEM ; SFLQHNKCEC ; RPKKDRARQE ; KKSVRGKGKG ; 200: QKRKRKKSRY ; KSWSVYVGAR ; CCLMPWSLPG ; PHPCGPCSER ; RKHLFVQDPQ ; 232: TCKCSCKNTD ; SRCKARQLEL ; NERTCRCDKP ; RR
Sequence Length	232
String	P15692
Sub Unit	Homodimer; disulfide-linked. Also found as heterodimer with PGF.

Uniprot	P15692
Gene Name	VEGFA
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:7422
Unigene	Hs.73793

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811943	E0143h	96T	$536		Add to Cart

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