Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury.
Specificity
Natural and recombinant Human Uveal autoantigen with coiled-coil domains and ankyrin repeats
Subcellular Location
Nucleus Cytoplasm Cytoplasm cytoskeleton Expressed diffusely in cytoplasm.
Component of the apoptosome complex, composed of APAF1, pro-caspase-9 and UACA. In the complex, it probably interacts directly with APAF1. Interacts with LGALS3, ARF6 and ACTB.