ELISA Kit for Human Tumor necrosis factor receptor superfamily member 14

Mfr.No.

E0294h

Alternative Names

Herpes virus entry mediator A ; Herpesvirus entry mediator A ; Tumor necrosis factor receptor-like 2 ; TR2 ; CD270 ; HVEA ; HVEM ; UNQ329/PRO509

Categories

Elisa

Function

Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.

Specificity

Natural and recombinant Human Tumor necrosis factor receptor superfamily member 14

Subcellular Location

Membrane Single-pass type I membrane protein

Detection Range

31.2-2000pg/mL

Entryname

TNR14_HUMAN

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	92-105%	90-101%	95-105%	92-109%
EDTA plasma(n=5)	89-95%	93105%	89-94%	90-106%
heparin plasma(n=5)	93-104%	94-110%	101-111%	91-110%

Method Type

Sandwich

Platform

PF00020

Precision

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤3.9%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤7.7%

Protein Name

Tumor necrosis factor receptor superfamily member 14

Recovery

Recovery was determined by spiking various levels of ACE into serum and plasma .

Sample Type	Average(%)	Recovery Range(%)
Serum	99	91-103
Plasma	98	93-106

Sensitivity

15pg/mL

Sequence

50:

MEPPGDWGPP ; PWRSTPKTDV ; LRLVLYLTFL ; GAPCYAPALP ; SCKEDEYPVG ;

100:

SECCPKCSPG ; YRVKEACGEL ; TGTVCEPCPP ; GTYIAHLNGL ; SKCLQCQMCD ;

150:

PAMGLRASRN ; CSRTENAVCG ; CSPGHFCIVQ ; DGDHCAACRA ; YATSSPGQRV ;

200:

QKGGTESQDT ; LCQNCPPGTF ; SPNGTLEECQ ; HQTKCSWLVT ; KAGAGTSSSH ;

250:

WVWWFLSGSL ; VIVIVCSTVG ; LIICVKRRKP ; RGDVVKVIVS ; VQRKRQEAEG ;

283:

EATVIEALQA ; PPDVTTVAVE ; ETIPSFTGRS ; PNH

Sequence Length

283

String

Q92956

Sub Unit

Interacts with TRAF2, TRAF3 and TRAF5. Interacts with herpes simplex virus 1 (HHV-1) and herpes simplex virus 1 (HHV-2) envelope glycoprotein D; functions as an entry receptor for these viruses.

Uniprot	Q92956
Gene Name	TNFRSF14
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:8764
Unigene	Hs.512898

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811144	E0294h	96T	$736		Add to Cart

ELISA Kit for Human Tumor necrosis factor receptor superfamily member 14

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