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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Transient receptor potential cation channel subfamily V member 1

SKU : BHE13811782

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E12152h
Alternative Names	Capsaicin receptor ; Osm-9-like TRP channel 1 ; OTRPC1 ; Vanilloid receptor 1 ; VR1
Categories	Elisa
Function	Receptor-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. May be involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Acts as ionotropic endocannabinoid receptor with central neuromodulatory effects. Triggers a form of long-term depression (TRPV1-LTD) mediated by the endocannabinoid anandamine in the hippocampus and nucleus accubens by affecting AMPA receptors endocytosis.
Specificity	Natural and recombinant Human Transient receptor potential cation channel subfamily V member 1
Subcellular Location	Cell junction synapse postsynaptic cell membrane Multi-pass membrane protein Cell projection dendritic spine membrane Multi-pass membrane protein
Detection Range	0.156-10ng/mL
Entryname	TRPV1_HUMAN
Method Type	Sandwich
Platform	PF12796
Protein Name	Transient receptor potential cation channel subfamily V member 1
Sensitivity	0.1ng/ml
Sequence	50: MKKWSSTDLG ; AAADPLQKDT ; CPDPLDGDPN ; SRPPPAKPQL ; STAKSRTRLF ; 100: GKGDSEEAFP ; VDCPHEEGEL ; DSCPTITVSP ; VITIQRPGDG ; PTGARLLSQD ; 150: SVAASTEKTL ; RLYDRRSIFE ; AVAQNNCQDL ; ESLLLFLQKS ; KKHLTDNEFK ; 200: DPETGKTCLL ; KAMLNLHDGQ ; NTTIPLLLEI ; ARQTDSLKEL ; VNASYTDSYY ; 250: KGQTALHIAI ; ERRNMALVTL ; LVENGADVQA ; AAHGDFFKKT ; KGRPGFYFGE ; 300: LPLSLAACTN ; QLGIVKFLLQ ; NSWQTADISA ; RDSVGNTVLH ; ALVEVADNTA ; 350: DNTKFVTSMY ; NEILMLGAKL ; HPTLKLEELT ; NKKGMTPLAL ; AAGTGKIGVL ; 400: AYILQREIQE ; PECRHLSRKF ; TEWAYGPVHS ; SLYDLSCIDT ; CEKNSVLEVI ; 450: AYSSSETPNR ; HDMLLVEPLN ; RLLQDKWDRF ; VKRIFYFNFL ; VYCLYMIIFT ; 500: MAAYYRPVDG ; LPPFKMEKTG ; DYFRVTGEIL ; SVLGGVYFFF ; RGIQYFLQRR ; 550: PSMKTLFVDS ; YSEMLFFLQS ; LFMLATVVLY ; FSHLKEYVAS ; MVFSLALGWT ; 600: NMLYYTRGFQ ; QMGIYAVMIE ; KMILRDLCRF ; MFVYIVFLFG ; FSTAVVTLIE ; 650: DGKNDSLPSE ; STSHRWRGPA ; CRPPDSSYNS ; LYSTCLELFK ; FTIGMGDLEF ; 700: TENYDFKAVF ; IILLLAYVIL ; TYILLLNMLI ; ALMGETVNKI ; AQESKNIWKL ; 750: QRAITILDTE ; KSFLKCMRKA ; FRSGKLLQVG ; YTPDGKDDYR ; WCFRVDEVNW ; 800: TTWNTNVGII ; NEDPGNCEGV ; KRTLSFSLRS ; SRVSGRHWKN ; FALVPLLREA ; 839: SARDRQSAQP ; EEVYLRQFSG ; SLKPEDAEVF ; KSPAASGEK
Sequence Length	839
String	Q8NER1
Sub Unit	Self-associates. Probably homotetramer. May also form a heteromeric channel with TRPV3. Interacts with calmodulin, PIRT, PRKCM and CSK. Interacts with PRKCG and NTRK1, probably by forming a trimeric complex.

Uniprot	Q8NER1
Gene Name	TRPV1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:7442
Unigene	Hs.579217

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811782	E12152h	96T	$736		Add to Cart

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