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ELISA Kit for Human Transcription initiation factor TFIID subunit 1

SKU : BHE13811636

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E8802h
Alternative Names	Cell cycle gene 1 protein ; TBP-associated factor 250 kDa ; p250 ; Transcription initiation factor TFIID 250 kDa subunit ; TAF(II)250 ; BA2R ; CCG1 ; CCGS ; TAF2A
Categories	Elisa
Function	Largest component and core scaffold of the TFIID basal transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle.
Specificity	Natural and recombinant Human Transcription initiation factor TFIID subunit 1
Subcellular Location	Nucleus
Detection Range	0.312-20ng/mL
Entryname	TAF1_HUMAN
Method Type	Sandwich
Platform	PF00439
Protein Name	Transcription initiation factor TFIID subunit 1
Sensitivity	0.12ng/mL
Sequence	50: MGPGCDLLLR ; TAATITAAAI ; MSDTDSDEDS ; AGGGPFSLAG ; FLFGNINGAG ; 100: QLEGESVLDD ; ECKKHLAGLG ; ALGLGSLITE ; LTANEELTGT ; DGALVNDEGW ; 150: VRSTEDAVDY ; SDINEVAEDE ; SRRYQQTMGS ; LQPLCHSDYD ; EDDYDADCED ; 200: IDCKLMPPPP ; PPPGPMKKDK ; DQDSITGEKV ; DFSSSSDSES ; EMGPQEATQA ; 250: ESEDGKLTLP ; LAGIMQHDAT ; KLLPSVTELF ; PEFRPGKVLR ; FLRLFGPGKN ; 300: VPSVWRSARR ; KRKKKHRELI ; QEEQIQEVEC ; SVESEVSQKS ; LWNYDYAPPP ; 350: PPEQCLSDDE ; ITMMAPVESK ; FSQSTGDIDK ; VTDTKPRVAE ; WRYGPARLWY ; 400: DMLGVPEDGS ; GFDYGFKLRK ; TEHEPVIKSR ; MIEEFRKLEE ; NNGTDLLADE ; 450: NFLMVTQLHW ; EDDIIWDGED ; VKHKGTKPQR ; ASLAGWLPSS ; MTRNAMAYNV ; 500: QQGFAATLDD ; DKPWYSIFPI ; DNEDLVYGRW ; EDNIIWDAQA ; MPRLLEPPVL ; 550: TLDPNDENLI ; LEIPDEKEEA ; TSNSPSKESK ; KESSLKKSRI ; LLGKTGVIKE ; 600: EPQQNMSQPE ; VKDPWNLSND ; EYYYPKQQGL ; RGTFGGNIIQ ; HSIPAVELRQ ; 650: PFFPTHMGPI ; KLRQFHRPPL ; KKYSFGALSQ ; PGPHSVQPLL ; KHIKKKAKMR ; 700: EQERQASGGG ; EMFFMRTPQD ; LTGKDGDLIL ; AEYSEENGPL ; MMQVGMATKI ; 750: KNYYKRKPGK ; DPGAPDCKYG ; ETVYCHTSPF ; LGSLHPGQLL ; QAFENNLFRA ; 800: PIYLHKMPET ; DFLIIRTRQG ; YYIRELVDIF ; VVGQQCPLFE ; VPGPNSKRAN ; 850: THIRDFLQVF ; IYRLFWKSKD ; RPRRIRMEDI ; KKAFPSHSES ; SIRKRLKLCA ; 900: DFKRTGMDSN ; WWVLKSDFRL ; PTEEEIRAMV ; SPEQCCAYYS ; MIAAEQRLKD ; 950: AGYGEKSFFA ; PEEENEEDFQ ; MKIDDEVRTA ; PWNTTRAFIA ; AMKGKCLLEV ; 1000: TGVADPTGCG ; EGFSYVKIPN ; KPTQQKDDKE ; PQPVKKTVTG ; TDADLRRLSL ; 1050: KNAKQLLRKF ; GVPEEEIKKL ; SRWEVIDVVR ; TMSTEQARSG ; EGPMSKFARG ; 1100: SRFSVAEHQE ; RYKEECQRIF ; DLQNKVLSST ; EVLSTDTDSS ; SAEDSDFEEM ; 1150: GKNIENMLQN ; KKTSSQLSRE ; REEQERKELQ ; RMLLAAGSAA ; SGNNHRDDDT ; 1200: ASVTSLNSSA ; TGRCLKIYRT ; FRDEEGKEYV ; RCETVRKPAV ; IDAYVRIRTT ; 1250: KDEEFIRKFA ; LFDEQHREEM ; RKERRRIQEQ ; LRRLKRNQEK ; EKLKGPPEKK ; 1300: PKKMKERPDL ; KLKCGACGAI ; GHMRTNKFCP ; LYYQTNAPPS ; NPVAMTEEQE ; 1350: EELEKTVIHN ; DNEELIKVEG ; TKIVLGKQLI ; ESADEVRRKS ; LVLKFPKQQL ; 1400: PPKKKRRVGT ; TVHCDYLNRP ; HKSIHRRRTD ; PMVTLSSILE ; SIINDMRDLP ; 1450: NTYPFHTPVN ; AKVVKDYYKI ; ITRPMDLQTL ; RENVRKRLYP ; SREEFREHLE ; 1500: LIVKNSATYN ; GPKHSLTQIS ; QSMLDLCDEK ; LKEKEDKLAR ; LEKAINPLLD ; 1550: DDDQVAFSFI ; LDNIVTQKMM ; AVPDSWPFHH ; PVNKKFVPDY ; YKVIVNPMDL ; 1600: ETIRKNISKH ; KYQSRESFLD ; DVNLILANSV ; KYNGPESQYT ; KTAQEIVNVC ; 1650: YQTLTEYDEH ; LTQLEKDICT ; AKEAALEEAE ; LESLDPMTPG ; PYTPQPPDLY ; 1700: DTNTSLSMSR ; DASVFQDESN ; MSVLDIPSAT ; PEKQVTQEGE ; DGDGDLADEE ; 1750: EGTVQQPQAS ; VLYEDLLMSE ; GEDDEEDAGS ; DEEGDNPFSA ; IQLSESGSDS ; 1800: DVGSGGIRPK ; QPRMLQENTR ; MDMENEESMM ; SYEGDGGEAS ; HGLEDSNISY ; 1850: GSYEEPDPKS ; NTQDTSFSSI ; GGYEVSEEEE ; DEEEEEQRSG ; PSVLSQVHLS ; 1872: EDEEDSEDFH ; SIAGDSDLDS ; DE
Sequence Length	1872
String	P21675
Sub Unit	TAF1 is the largest component of transcription factor TFIID that is composed of TBP and a variety of TBP-associated factors. TAF1, when part of the TFIID complex, interacts with C-terminus of TP53. Component of some MLL1/MLL complex, at least composed of the core components MLL, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components C17orf49, CHD8, E2F6, HSP70, IN80C, KIAA1267, LAS1L, MAX, MCRS1, MGA, KAT8/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. RB1 interacts with the N-terminal domain of TAF1. Interacts with ASF1A and ASF1B. Interacts with SV40 Large T antigen.

Uniprot	P21675
Gene Name	TAF1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:6872
Unigene	Hs.158560

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BHE13811636	E8802h	96T	$736		Add to Cart

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