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Home / Assay Kits / ELISA Kits

ELISA Kit for Human TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

SKU : BHE13809718

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E2882h
Alternative Names	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 ; TAK1-binding protein 2 ; TAB-2 ; TGF-beta-activated kinase 1-binding protein 2 ; KIAA0733 ; MAP3K7IP2
Categories	Elisa
Function	Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'-linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development.
Specificity	Natural and recombinant Human TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
Subcellular Location	Membrane Peripheral membrane protein Cytoplasm cytosol Following IL1 stimulation, translocation occurs from the membrane to cytosol.
Detection Range	15.6-1000pg/mL
Entryname	TAB2_HUMAN
Method Type	Sandwich
Platform	PF02845
Protein Name	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
Sensitivity	10pg/mL
Sequence	50: MAQGSHQIDF ; QVLHDLRQKF ; PEVPEVVVSR ; CMLQNNNNLD ; ACCAVLSQES ; 100: TRYLYGEGDL ; NFSDDSGISG ; LRNHMTSLNL ; DLQSQNIYHH ; GREGSRMNGS ; 150: RTLTHSISDG ; QLQGGQSNSE ; LFQQEPQTAP ; AQVPQGFNVF ; GMSSSSGASN ; 200: SAPHLGFHLG ; SKGTSSLSQQ ; TPRFNPIMVT ; LAPNIQTGRN ; TPTSLHIHGV ; 250: PPPVLNSPQG ; NSIYIRPYIT ; TPGGTTRQTQ ; QHSGWVSQFN ; PMNPQQVYQP ; 300: SQPGPWTTCP ; ASNPLSHTSS ; QQPNQQGHQT ; SHVYMPISSP ; TTSQPPTIHS ; 350: SGSSQSSAHS ; QYNIQNISTG ; PRKNQIEIKL ; EPPQRNNSSK ; LRSSGPRTSS ; 400: TSSSVNSQTL ; NRNQPTVYIA ; ASPPNTDELM ; SRSQPKVYIS ; ANAATGDEQV ; 450: MRNQPTLFIS ; TNSGASAASR ; NMSGQVSMGP ; AFIHHHPPKS ; RAIGNNSATS ; 500: PRVVVTQPNT ; KYTFKITVSP ; NKPPAVSPGV ; VSPTFELTNL ; LNHPDHYVET ; 550: ENIQHLTDPT ; LAHVDRISET ; RKLSMGSDDA ; AYTQALLVHQ ; KARMERLQRE ; 600: LEIQKKKLDK ; LKSEVNEMEN ; NLTRRRLKRS ; NSISQIPSLE ; EMQQLRSCNR ; 650: QLQIDIDCLT ; KEIDLFQARG ; PHFNPSAIHN ; FYDNIGFVGP ; VPPKPKDQRS ; 693: IIKTPKTQDT ; EDDEGAQWNC ; TACTFLNHPA ; LIRCEQCEMP ; RHF
Sequence Length	693
String	Q9NYJ8
Sub Unit	Interacts with MAP3K7 and TRAF6. Identified in the TRIKA2 complex composed of MAP3K7, TAB1 and TAB2. Binds 'Lys-63'-linked polyubiquitin chains. Interacts with NCOR1 and HDAC3 to form a ternary complex. Interacts (via C-terminal) with NUMBL (via PTB domain). Interacts (via the C-terminus) with WDR34 (via WD domains). Interacts with RBCK1.

Uniprot	Q9NYJ8
Gene Name	TAB2
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:23118
Unigene	Hs.269775

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809718	E2882h	96T	$736		Add to Cart

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