As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity.
Specificity
Natural and recombinant Human Talin-2
Subcellular Location
Cell junction focal adhesion Cell junction synapse Cell membrane Peripheral membrane protein Cytoplasmic side Cytoplasm cytoskeleton Focal adhesion plaques and synapses.