ELISA Kit for Human Suppressor of cytokine signaling 2

Mfr.No.	E1415h
Alternative Names	Cytokine-inducible SH2 protein 2 ; CIS-2 ; STAT-induced STAT inhibitor 2 ; SSI-2 ; CIS2 ; SSI2 ; STATI2
Categories	Elisa
Function	SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Specificity	Natural and recombinant Human Suppressor of cytokine signaling 2
Detection Range	125-8000pg/mL
Entryname	SOCS2_HUMAN
Method Type	Sandwich
Platform	PF00017
Protein Name	Suppressor of cytokine signaling 2
Sensitivity	56pg/mL
Sequence	50: MTLRCLEPSG ; NGGEGTRSQW ; GTAGSAEEPS ; PQAARLAKAL ; RELGQTGWYW ; 100: GSMTVNEAKE ; KLKEAPEGTF ; LIRDSSHSDY ; LLTISVKTSA ; GPTNLRIEYQ ; 150: DGKFRLDSII ; CVKSKLKQFD ; SVVHLIDYYV ; QMCKDKRTGP ; EAPRNGTVHL ; 198: YLTKPLYTSA ; PSLQHLCRLT ; INKCTGAIWG ; LPLPTRLKDY ; LEEYKFQV
Sequence Length	198
String	O14508
Sub Unit	Interacts with IGF1 receptor, prolactin receptor and growth hormone (GH) receptor. Associates with the Elongin BC complex.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810831	E1415h	96T	$736		Add to Cart