ELISA Kit for Human SUMO-activating enzyme subunit 1

Mfr.No.	E3292h
Alternative Names	Ubiquitin-like 1-activating enzyme E1A ; AOS1 ; SUA1 ; UBLE1A
Categories	Elisa
Function	The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Specificity	Natural and recombinant Human SUMO-activating enzyme subunit 1
Subcellular Location	Nucleus
Detection Range	0.156-10ng/mL
Entryname	SAE1_HUMAN
Method Type	Sandwich
Platform	PF00899
Protein Name	SUMO-activating enzyme subunit 1
Sensitivity	0.078ng/mL
Sequence	50: MVEKEEAGGG ; ISEEEAAQYD ; RQIRLWGLEA ; QKRLRASRVL ; LVGLKGLGAE ; 100: IAKNLILAGV ; KGLTMLDHEQ ; VTPEDPGAQF ; LIRTGSVGRN ; RAEASLERAQ ; 150: NLNPMVDVKV ; DTEDIEKKPE ; SFFTQFDAVC ; LTCCSRDVIV ; KVDQICHKNS ; 200: IKFFTGDVFG ; YHGYTFANLG ; EHEFVEEKTK ; VAKVSQGVED ; GPDTKRAKLD ; 250: SSETTMVKKK ; VVFCPVKEAL ; EVDWSSEKAK ; AALKRTTSDY ; FLLQVLLKFR ; 300: TDKGRDPSSD ; TYEEDSELLL ; QIRNDVLDSL ; GISPDLLPED ; FVRYCFSEMA ; 346: PVCAVVGGIL ; AQEIVKALSQ ; RDPPHNNFFF ; FDGMKGNGIV ; ECLGPK
Sequence Length	346
String	Q9UBE0
Sub Unit	Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810141	E3292h	96T	$736		Add to Cart