Modulator of antigen receptor signaling ; MARS ; Src-like adapter protein 2 ; SLAP-2 ; C20orf156 ; SLAP2
Categories
Elisa
Function
Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.
Specificity
Natural and recombinant Human Src-like-adapter 2
Subcellular Location
Isoform 2 Cytoplasm May be cytoplasmic and is not localized to membranes.