ELISA Kit for Human Sphingosine 1-phosphate receptor 2

Mfr.No.	E0325h
Alternative Names	Endothelial differentiation G-protein coupled receptor 5 ; Sphingosine 1-phosphate receptor Edg-5 ; S1P receptor Edg-5 ; EDG5
Categories	Elisa
Function	Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.
Specificity	Natural and recombinant Human Sphingosine 1-phosphate receptor 2
Subcellular Location	Cell membrane Multi-pass membrane protein
Detection Range	0.625-40ng/mL
Entryname	S1PR2_HUMAN
Method Type	Sandwich
Platform	PF00001
Protein Name	Sphingosine 1-phosphate receptor 2
Sensitivity	0.22ng/mL
Sequence	50: MGSLYSEYLN ; PNKVQEHYNY ; TKETLETQET ; TSRQVASAFI ; VILCCAIVVE ; 100: NLLVLIAVAR ; NSKFHSAMYL ; FLGNLAASDL ; LAGVAFVANT ; LLSGSVTLRL ; 150: TPVQWFAREG ; SAFITLSASV ; FSLLAIAIER ; HVAIAKVKLY ; GSDKSCRMLL ; 200: LIGASWLISL ; VLGGLPILGW ; NCLGHLEACS ; TVLPLYAKHY ; VLCVVTIFSI ; 250: ILLAIVALYV ; RIYCVVRSSH ; ADMAAPQTLA ; LLKTVTIVLG ; VFIVCWLPAF ; 300: SILLLDYACP ; VHSCPILYKA ; HYFFAVSTLN ; SLLNPVIYTW ; RSRDLRREVL ; 350: RPLQCWRPGV ; GVQGRRRGGT ; PGHHLLPLRS ; SSSLERGMHM ; PTSPTFLEGN ; 353: TVV
Sequence Length	353
String	O95136

Reference	1. "Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5." An S., Zheng Y., Bleu T. J. Biol. Chem.275:288-296(2000) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Fetal brain. 2. "cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)." Kopatz S.A., Aronstam R.S., Sharma S.V. Submitted (2003-03) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] 3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]

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