Calcium-binding protein that modulates excitation-contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels.
Specificity
Natural and recombinant Human Sorcin
Subcellular Location
Cytoplasm Sarcoplasmic reticulum membrane Peripheral membrane protein Cytoplasmic side Relocates to the sarcoplasmic reticulum membrane in response to elevated calcium levels.