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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Segment polarity protein dishevelled homolog DVL-1

SKU : BHE13803508

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15104h
Alternative Names	DSH homolog 1
Categories	Elisa
Function	Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling.
Specificity	Natural and recombinant Human Segment polarity protein dishevelled homolog DVL-1
Subcellular Location	Cell membrane Peripheral membrane protein Cytoplasmic side Cytoplasm cytosol Cytoplasmic vesicle Localizes at the cell membrane upon interaction with frizzled family members.
Detection Range	0.156-10ng/mL
Entryname	DVL1_HUMAN
Method Type	Sandwich
Platform	PF00610
Protein Name	Segment polarity protein dishevelled homolog DVL-1
Sensitivity	0.021ng/ml
Sequence	50: MAETKIIYHM ; DEEETPYLVK ; LPVAPERVTL ; ADFKNVLSNR ; PVHAYKFFFK ; 100: SMDQDFGVVK ; EEIFDDNAKL ; PCFNGRVVSW ; LVLAEGAHSD ; AGSQGTDSHT ; 150: DLPPPLERTG ; GIGDSRPPSF ; HPNVASSRDG ; MDNETGTESM ; VSHRRERARR ; 200: RNREEAARTN ; GHPRGDRRRD ; VGLPPDSAST ; ALSSELESSS ; FVDSDEDGST ; 250: SRLSSSTEQS ; TSSRLIRKHK ; RRRRKQRLRQ ; ADRASSFSSI ; TDSTMSLNIV ; 300: TVTLNMERHH ; FLGISIVGQS ; NDRGDGGIYI ; GSIMKGGAVA ; ADGRIEPGDM ; 350: LLQVNDVNFE ; NMSNDDAVRV ; LREIVSQTGP ; ISLTVAKCWD ; PTPRSYFTVP ; 400: RADPVRPIDP ; AAWLSHTAAL ; TGALPRYGTS ; PCSSAVTRTS ; SSSLTSSVPG ; 450: APQLEEAPLT ; VKSDMSAVVR ; VMQLPDSGLE ; IRDRMWLKIT ; IANAVIGADV ; 500: VDWLYTHVEG ; FKERREARKY ; ASSLLKHGFL ; RHTVNKITFS ; EQCYYVFGDL ; 550: CSNLATLNLN ; SGSSGTSDQD ; TLAPLPHPAA ; PWPLGQGYPY ; QYPGPPPCFP ; 600: PAYQDPGFSY ; GSGSTGSQQS ; EGSKSSGSTR ; SSRRAPGREK ; ERRAAGAGGS ; 650: GSESDHTAPS ; GVGSSWRERP ; AGQLSRGSSP ; RSQASATAPG ; LPPPHPTTKA ; 695: YTVVGGPPGG ; PPVRELAAVP ; PELTGSRQSF ; QKAMGNPCEF ; FVDIM
Sequence Length	695
String	O14640
Sub Unit	Interacts with CXXC4. Interacts (via PDZ domain) with NXN (By similarity). Interacts with BRD7 and INVS. Interacts through its PDZ domain with the C-terminal regions of VANGL1, VANGL2 and CCDC88C/DAPLE. Interacts with ARRB1; the interaction is enhanced by phosphorylation of DVL1. Interacts with CYLD (By similarity). Interacts (via PDZ domain) with RYK. Self-associates (via DIX domain) and forms higher homooligomers. Interacts (via PDZ domain) with DACT1 and FZD7, where DACT1 and FZD7 compete for the same binding site.

Uniprot	O14640
Gene Name	DVL1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:1855
Unigene	Hs.731450

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SKU	Supplier No.	Size	Your price	Quantity
BHE13803508	E15104h	96T	$736		Add to Cart

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