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ELISA Kit for Human Secreted frizzled-related protein 2

SKU : BHE13810498

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0450h
Alternative Names	Secreted apoptosis-related protein 1 ; SARP-1 ; FRP2 ; SARP1 ; FKSG12 ; UNQ361/PRO697
Categories	Elisa
Function	Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.
Specificity	Natural and recombinant Human Secreted frizzled-related protein 2
Subcellular Location	Secreted
Detection Range	1.25-80ng/mL
Entryname	SFRP2_HUMAN
Method Type	Sandwich
Platform	PF01392
Protein Name	Secreted frizzled-related protein 2
Sensitivity	0.65ng/mL
Sequence	50: MLQGPGSLLL ; LFLASHCCLG ; SARGLFLFGQ ; PDFSYKRSNC ; KPIPANLQLC ; 100: HGIEYQNMRL ; PNLLGHETMK ; EVLEQAGAWI ; PLVMKQCHPD ; TKKFLCSLFA ; 150: PVCLDDLDET ; IQPCHSLCVQ ; VKDRCAPVMS ; AFGFPWPDML ; ECDRFPQDND ; 200: LCIPLASSDH ; LLPATEEAPK ; VCEACKNKND ; DDNDIMETLC ; KNDFALKIKV ; 250: KEITYINRDT ; KIILETKSKT ; IYKLNGVSER ; DLKKSVLWLK ; DSLQCTCEEM ; 295: NDINAPYLVM ; GQKQGGELVI ; TSVKRWQKGQ ; REFKRISRSI ; RKLQC
Sequence Length	295
String	Q96HF1

Uniprot	Q96HF1
Gene Name	SFRP2
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:6423
Unigene	Hs.481022

Reference	1. "Tissue restricted expression of two human Frzbs in preadipocytes and pancreas." Hu E., Zhu Y., Fredrickson T., Barnes M., Kelsell D., Beeley L., Brooks D. Biochem. Biophys. Res. Commun.247:287-293(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY 2. "Characterization of FKSG12, a novel protein related to pancreas tumor." Wang Y.-G. Submitted (2000-10) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 3. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J., Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P., Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E., Heldens S., Huang A., Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D., Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L., Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C., Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J., Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M.more... Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT VAL-45 4. "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries." Otsuki T., Ota T., Nishikawa T., Hayashi K., Suzuki Y., Yamamoto J., Wakamatsu A., Kimura K., Sakamoto K., Hatano N., Kawai Y., Ishii S., Saito K., Kojima S., Sugiyama T., Ono T., Okano K., Yoshikawa Y., Aotsuka S., Sasaki N., Hattori A., Okumura K., Nagai K., Sugano S., Isogai T.more... DNA Res.12:117-126(2005) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] 5. Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.more... Submitted (2005-09) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT VAL-45 tissue: Eye. 7. "SARPs: a family of secreted apoptosis-related proteins." Melkonyan H.S., Chang W.C., Shapiro J.P., Mahadevappa M., Fitzpatrick P.A., Kiefer M.C., Tomei L.D., Umansky S.R. Proc. Natl. Acad. Sci. U.S.A.94:13636-13641(1997) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-208;TISSUE SPECIFICITY 8. "Signal peptide prediction based on analysis of experimentally verified cleavage sites." Zhang Z., Henzel W.J. Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-39

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