After shedding, the soluble form (sCD163) may play an anti-inflammatory role, and may be a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions.
Specificity
Natural and recombinant Human Scavenger receptor cysteine-rich type 1 protein M130
Subcellular Location
Cell membrane Single-pass type I membrane protein Isoform 1 and isoform 2 show a lower surface expression when expressed in cells.