ELISA Kit for Human RING-box protein 2

Mfr.No.	E11416h
Alternative Names	CKII beta-binding protein 1 ; CKBBP1 ; RING finger protein 7 ; Regulator of cullins 2 ; Sensitive to apoptosis gene protein ; RBX2 ; ROC2 ; SAG
Categories	Elisa
Function	Probable component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.
Specificity	Natural and recombinant Human RING-box protein 2
Subcellular Location	Cytoplasm Nucleus
Detection Range	0.312-20ng/ml
Entryname	RBX2_HUMAN
Method Type	Sandwich
Platform	PF12678
Protein Name	RING-box protein 2
Sensitivity	0.16ng/mL
Sequence	50: MADVEDGEET ; CALASHSGSS ; GSKSGGDKMF ; SLKKWNAVAM ; WSWDVECDTC ; 100: AICRVQVMDA ; CLRCQAENKQ ; EDCVVVWGEC ; NHSFHNCCMS ; LWVKQNNRCP ; 113: LCQQDWVVQR ; IGK
Sequence Length	113
String	Q9UBF6
Sub Unit	Probable part of SCF complexes, which consist of SKP1, CUL1, RNF7/RBX2 and a F-box protein. Interacts (preferentially) with CUL5. Also interacts (with lower preference) with CUL1, CUL2, CUL3, CUL4A and CUL4B. Interacts with UBE2F. Interacts with CSNK2B, the interaction is not affected by phosphorylation by CK2.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810209	E11416h	96T	$736		Add to Cart