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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Rho guanine nucleotide exchange factor 7

SKU : BHE13801375

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E14325h
Alternative Names	Beta-Pix ; COOL-1 ; PAK-interacting exchange factor beta ; p85 ; COOL1 ; KIAA0142 ; P85SPR ; PAK3BP ; PIXB ; Nbla10314
Categories	Elisa
Function	Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. May function as a positive regulator of apoptosis. May function in cell migration. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
Specificity	Natural and recombinant Human Rho guanine nucleotide exchange factor 7
Entryname	ARHG7_HUMAN
Platform	PF00307
Protein Name	Rho guanine nucleotide exchange factor 7
Sequence	50: MNSAEQTVTW ; LITLGVLESP ; KKTISDPEGF ; LQASLKDGVV ; LCRLLERLLP ; 100: GTIEKVYPEP ; RSESECLSNI ; REFLRGCGAS ; LRLELLFPPS ; QPPQHLVTTI ; 150: LLSASTFDAN ; DLYQGQNFNK ; VLSSLVTLNK ; VTADIGLGSD ; SVCARPSSHR ; 200: IKSFDSLGSQ ; SLHTRTSKLF ; QGQYRSLDMT ; DNSNNQLVVR ; AKFNFQQTNE ; 250: DELSFSKGDV ; IHVTRVEEGG ; WWEGTLNGRT ; GWFPSNYVRE ; VKASEKPVSP ; 300: KSGTLKSPPK ; GFDTTAINKS ; YYNVVLQNIL ; ETENEYSKEL ; QTVLSTYLRP ; 350: LQTSEKLSSA ; NISYLMGNLE ; EICSFQQMLV ; QSLEECTKLP ; EAQQRVGGCF ; 400: LNLMPQMKTL ; YLTYCANHPS ; AVNVLTEHSE ; ELGEFMETKG ; ASSPGILVLT ; 450: TGLSKPFMRL ; DKYPTLLKEL ; ERHMEDYHTD ; RQDIQKSMAA ; FKNLSAQCQE ; 500: VRKRKELELQ ; ILTEAIRNWE ; GDDIKTLGNV ; TYMSQVLIQC ; AGSEEKNERY ; 550: LLLFPNVLLM ; LSASPRMSGF ; IYQGKLPTTG ; MTITKLEDSE ; NHRNAFEISG ; 600: SMIERILVSC ; NNQQDLQEWV ; EHLQKQTKVT ; SVGNPTIKPH ; SVPSHTLPSH ; 650: PVTPSSKHAD ; SKPAPLTPAY ; HTLPHPSHHG ; TPHTTINWGP ; LEPPKTPKPW ; 700: SLSCLRPAPP ; LRPSAALCYK ; EDLSKSPKTM ; KKLLPKRKPE ; RKPSDEEFAS ; 750: RKSTAALEED ; AQILKVIEAY ; CTSAKTRQTL ; NSTWQGTDLM ; HNHVLADDDQ ; 800: PSLDSLGRRS ; SLSRLEPSDL ; SEDSDYDSIW ; TAHSYRMGST ; SRKSCCSYIS ; 803: HQN
Sequence Length	803
String	Q14155
Sub Unit	Interacts with PAK kinases through the SH3 domain. Interacts with GIT1 and TGFB1I1. Interacts with ITCH (By similarity). Interacts with unphosphorylated PAK1. Interacts with SCRIB; interaction is direct and may play a role in regulation of apoptosis. Interacts with FRMPD4 (via N-terminus). Interacts with CaMK1.

Uniprot	Q14155
Gene Name	ARHGEF7
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:8874
Unigene	Hs.508738

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SKU	Supplier No.	Size	Your price	Quantity
BHE13801375	E14325h	96T	$736		Add to Cart

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