Modulates the activity of cell cycle-specific kinases. Enhances CDK1 activity. May contribute to the regulation of the cell cycle. May inhibit growth of glioma cells by promoting arrest of mitotic progression at the G2/M transition.
Specificity
Natural and recombinant Human Response gene to complement 32 protein
Subcellular Location
Cytoplasm Nucleus Cytoplasm cytoskeleton centrosome Cytoplasmic in unstimulated cells. Nuclear after activation by complement. Associated with the centrosome during prometaphase and metaphase.