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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Receptor-type tyrosine-protein phosphatase C

SKU : BHE13809401

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1030h
Antigen	PTPRC
Alternative Names	Leukocyte common antigen ; L-CA ; T200 ; CD45 ; CD45
Categories	Elisa
Function	Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN.
Specificity	Natural and recombinant Human Receptor-type tyrosine-protein phosphatase C
Subcellular Location	Membrane Single-pass type I membrane protein Membrane raft Colocalized with DPP4 in membrane rafts.
Detection Range	0.156-10ng/mL
Entryname	PTPRC_HUMAN
Method Type	Sandwich
Platform	PF00041
Protein Name	Receptor-type tyrosine-protein phosphatase C
Sensitivity	0.081ng/mL
Sequence	50: MYLWLKLLAF ; GFAFLDTEVF ; VTGQSPTPSP ; TGLTTAKMPS ; VPLSSDPLPT ; 100: HTTAFSPAST ; FERENDFSET ; TTSLSPDNTS ; TQVSPDSLDN ; ASAFNTTGVS ; 150: SVQTPHLPTH ; ADSQTPSAGT ; DTQTFSGSAA ; NAKLNPTPGS ; NAISDVPGER ; 200: STASTFPTDP ; VSPLTTTLSL ; AHHSSAALPA ; RTSNTTITAN ; TSDAYLNASE ; 250: TTTLSPSGSA ; VISTTTIATT ; PSKPTCDEKY ; ANITVDYLYN ; KETKLFTAKL ; 300: NVNENVECGN ; NTCTNNEVHN ; LTECKNASVS ; ISHNSCTAPD ; KTLILDVPPG ; 350: VEKFQLHDCT ; QVEKADTTIC ; LKWKNIETFT ; CDTQNITYRF ; QCGNMIFDNK ; 400: EIKLENLEPE ; HEYKCDSEIL ; YNNHKFTNAS ; KIIKTDFGSP ; GEPQIIFCRS ; 450: EAAHQGVITW ; NPPQRSFHNF ; TLCYIKETEK ; DCLNLDKNLI ; KYDLQNLKPY ; 500: TKYVLSLHAY ; IIAKVQRNGS ; AAMCHFTTKS ; APPSQVWNMT ; VSMTSDNSMH ; 550: VKCRPPRDRN ; GPHERYHLEV ; EAGNTLVRNE ; SHKNCDFRVK ; DLQYSTDYTF ; 600: KAYFHNGDYP ; GEPFILHHST ; SYNSKALIAF ; LAFLIIVTSI ; ALLVVLYKIY ; 650: DLHKKRSCNL ; DEQQELVERD ; DEKQLMNVEP ; IHADILLETY ; KRKIADEGRL ; 700: FLAEFQSIPR ; VFSKFPIKEA ; RKPFNQNKNR ; YVDILPYDYN ; RVELSEINGD ; 750: AGSNYINASY ; IDGFKEPRKY ; IAAQGPRDET ; VDDFWRMIWE ; QKATVIVMVT ; 800: RCEEGNRNKC ; AEYWPSMEEG ; TRAFGDVVVK ; INQHKRCPDY ; IIQKLNIVNK ; 850: KEKATGREVT ; HIQFTSWPDH ; GVPEDPHLLL ; KLRRRVNAFS ; NFFSGPIVVH ; 900: CSAGVGRTGT ; YIGIDAMLEG ; LEAENKVDVY ; GYVVKLRRQR ; CLMVQVEAQY ; 950: ILIHQALVEY ; NQFGETEVNL ; SELHPYLHNM ; KKRDPPSEPS ; PLEAEFQRLP ; 1000: SYRSWRTQHI ; GNQEENKSKN ; RNSNVIPYDY ; NRVPLKHELE ; MSKESEHDSD ; 1050: ESSDDDSDSE ; EPSKYINASF ; IMSYWKPEVM ; IAAQGPLKET ; IGDFWQMIFQ ; 1100: RKVKVIVMLT ; ELKHGDQEIC ; AQYWGEGKQT ; YGDIEVDLKD ; TDKSSTYTLR ; 1150: VFELRHSKRK ; DSRTVYQYQY ; TNWSVEQLPA ; EPKELISMIQ ; VVKQKLPQKN ; 1200: SSEGNKHHKS ; TPLLIHCRDG ; SQQTGIFCAL ; LNLLESAETE ; EVVDIFQVVK ; 1250: ALRKARPGMV ; STFEQYQFLY ; DVIASTYPAQ ; NGQVKKNNHQ ; EDKIEFDNEV ; 1300: DKVKQDANCV ; NPLGAPEKLP ; EAKEQAEGSE ; PTSGTEGPEH ; SVNGPASPAL ; 1304: NQGS
Sequence Length	1304
String	P08575
Sub Unit	Binds GANAB and PRKCSH (By similarity). Interacts with SKAP1. Interacts with DPP4; the interaction is enhanced in a interleukin-12-dependent manner in activated lymphocytes.

Uniprot	P08575
Gene Name	PTPRC
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:5788
Unigene	Hs.654514

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809401	E1030h	96T	$736		Add to Cart

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