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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Radical S-adenosyl methionine domain-containing protein 2

SKU : BHE13809178

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E3787h
Alternative Names	Cytomegalovirus-induced gene 5 protein ; Viperin ; Virus inhibitory protein ; endoplasmic reticulum-associated ; interferon-inducible ; CIG5
Categories	Elisa
Function	Involved in antiviral defense. May impair virus budding by disrupting lipid rafts at the plasma membrane, a feature which is essential for the budding process of many viruses. Acts through binding with and inactivating FPPS, an enzyme involved in synthesis of cholesterol, farnesylated and geranylated proteins, ubiquinones dolichol and heme. Plays a major role in the cell antiviral state induced by type I and type II interferon. Displays antiviral effect against HIV-1 virus, hepatitis C virus, human cytomegalovirus, and aphaviruses, but not vesiculovirus.
Specificity	Natural and recombinant Human Radical S-adenosyl methionine domain-containing protein 2
Subcellular Location	Endoplasmic reticulum membrane Peripheral membrane protein Cytoplasmic side Golgi apparatus Probably associates with the cytosolic side of the endoplasmic reticulum. Infection with human cytomegalovirus (HCMV) causes relocation to the Golgi apparatus and to cytoplasmic vacuoles which also contain HCMV proteins glycoprotein B and pp28.
Detection Range	0.78-50ng/mL
Entryname	RSAD2_HUMAN
Method Type	Sandwich
Platform	PF04055
Protein Name	Radical S-adenosyl methionine domain-containing protein 2
Sensitivity	0.072ng/mL
Sequence	50: MWVLTPAAFA ; GKLLSVFRQP ; LSSLWRSLVP ; LFCWLRATFW ; LLATKRRKQQ ; 100: LVLRGPDETK ; EEEEDPPLPT ; TPTSVNYHFT ; RQCNYKCGFC ; FHTAKTSFVL ; 150: PLEEAKRGLL ; LLKEAGMEKI ; NFSGGEPFLQ ; DRGEYLGKLV ; RFCKVELRLP ; 200: SVSIVSNGSL ; IRERWFQNYG ; EYLDILAISC ; DSFDEEVNVL ; IGRGQGKKNH ; 250: VENLQKLRRW ; CRDYRVAFKI ; NSVINRFNVE ; EDMTEQIKAL ; NPVRWKVFQC ; 300: LLIEGENCGE ; DALREAERFV ; IGDEEFERFL ; ERHKEVSCLV ; PESNQKMKDS ; 350: YLILDEYMRF ; LNCRKGRKDP ; SKSILDVGVE ; EAIKFSGFDE ; KMFLKRGGKY ; 361: IWSKADLKLD ; W
Sequence Length	361
String	Q8WXG1
Sub Unit	Interacts with FPPS.

Uniprot	Q8WXG1
Gene Name	RSAD2
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:91543
Unigene	Hs.17518

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809178	E3787h	96T	$736		Add to Cart

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