In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.
Specificity
Natural and recombinant Human Pulmonary surfactant-associated protein A1
Subcellular Location
Secreted extracellular space extracellular matrix Secreted extracellular space surface film