CGRP ; Calcium-binding protein in amniotic fluid 1 ; CAAF1 ; Calgranulin-C ; CAGC ; Extracellular newly identified RAGE-binding protein ; EN-RAGE ; Migration inhibitory factor-related protein 6 ; MRP-6 ; Neutrophil S100 protein ; S100 calcium-binding protein A12
Categories
Elisa
Function
Calcitermin possesses antifungal activity against C.albicans and is also active against E.coli and P.aeruginosa but not L.monocytogenes and S.aureus. Binds calcium, zinc and copper. Presence of zinc increases the affinity for calcium. Plays an important role in the inflammatory response. Interaction with AGER on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators.
Homodimer. Homooligomer (tetramer or hexamer) in the presence of calcium and zinc ions. Interacts with AGER and both calcium and zinc are essential for the interaction.