ARPP-binding protein ; Cytosolic leucine-rich protein ; PIGEA-14 ; PKD2 interactor ; Golgi and endoplasmic reticulum-associated 1 ; ARB1 ; C22orf2 ; CBY ; PGEA1 ; HRIHFB2025
Categories
Elisa
Function
Inhibits the Wnt/Wingless pathway by binding to beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.
Specificity
Natural and recombinant Human Protein chibby homolog 1
Subcellular Location
Nucleus speckle Golgi apparatus trans-Golgi network Nuclear, in a punctate manner. Also found in the trans-Golgi.