ELISA Kit for Human Protein atonal homolog 1

Mfr.No.	E0255h
Alternative Names	Class A basic helix-loop-helix protein 14 ; bHLHa14 ; Helix-loop-helix protein hATH-1 ; hATH1 ; ATH1 ; BHLHA14
Categories	Elisa
Function	Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription.
Specificity	Natural and recombinant Human Protein atonal homolog 1
Subcellular Location	Nucleus
Detection Range	0.78-50ng/mL
Entryname	ATOH1_HUMAN
Method Type	Sandwich
Platform	PF00010
Protein Name	Protein atonal homolog 1
Sensitivity	0.33ng/mL
Sequence	50: MSRLLHAEEW ; AEVKELGDHH ; RQPQPHHLPQ ; PPPPPQPPAT ; LQAREHPVYP ; 100: PELSLLDSTD ; PRAWLAPTLQ ; GICTARAAQY ; LLHSPELGAS ; EAAAPRDEVD ; 150: GRGELVRRSS ; GGASSSKSPG ; PVKVREQLCK ; LKGGVVVDEL ; GCSRQRAPSS ; 200: KQVNGVQKQR ; RLAANARERR ; RMHGLNHAFD ; QLRNVIPSFN ; NDKKLSKYET ; 250: LQMAQIYINA ; LSELLQTPSG ; GEQPPPPPAS ; CKSDHHHLRT ; AASYEGGAGN ; 300: ATAAGAQQAS ; GGSQRPTPPG ; SCRTRFSAPA ; SAGGYSVQLD ; ALHFSTFEDS ; 350: ALTAMMAQKN ; LSPSLPGSIL ; QPVQEENSKT ; SPRSHRSDGE ; FSPHSHYSDS ; 354: DEAS
Sequence Length	354
String	Q92858
Sub Unit	Efficient DNA binding requires dimerization with another bHLH protein.

Reference	1. "Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesis." Ben-Arie N., McCall A.E., Berkman S., Eichele G., Bellen H.J., Zoghbi H.Y. Hum. Mol. Genet.5:1207-1216(1996) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] 2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]

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SKU	Supplier No.	Size	Your price	Quantity
BHE13801525	E0255h	96T	$736		Add to Cart