ELISA Kit for Human Prohibitin-2

Mfr.No.	E12515h
Alternative Names	B-cell receptor-associated protein BAP37 ; D-prohibitin ; Repressor of estrogen receptor activity ; BAP ; REA
Categories	Elisa
Function	Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
Specificity	Natural and recombinant Human Prohibitin-2
Subcellular Location	Mitochondrion inner membrane Cytoplasm Nucleus Also cytoplasmic and nuclear.
Detection Range	0.156-10ng/mL
Entryname	PHB2_HUMAN
Method Type	Sandwich
Platform	PF01145
Protein Name	Prohibitin-2
Sensitivity	0.08ng/mL
Sequence	50: MAQNLKDLAG ; RLPAGPRGMG ; TALKLLLGAG ; AVAYGVRESV ; FTVEGGHRAI ; 100: FFNRIGGVQQ ; DTILAEGLHF ; RIPWFQYPII ; YDIRARPRKI ; SSPTGSKDLQ ; 150: MVNISLRVLS ; RPNAQELPSM ; YQRLGLDYEE ; RVLPSIVNEV ; LKSVVAKFNA ; 200: SQLITQRAQV ; SLLIRRELTE ; RAKDFSLILD ; DVAITELSFS ; REYTAAVEAK ; 250: QVAQQEAQRA ; QFLVEKAKQE ; QRQKIVQAEG ; EAEAAKMLGE ; ALSKNPGYIK ; 299: LRKIRAAQNI ; SKTIATSQNR ; IYLTADNLVL ; NLQDESFTRG ; SDSLIKGKK
Sequence Length	299
String	Q99623
Sub Unit	Interacts with PHB, ESR1, HDAC1 and HDAC5 (By similarity). Interacts with ZNF703.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808567	E12515h	96T	$736		Add to Cart