The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis.
Specificity
Natural and recombinant Human Platelet glycoprotein V
"Single novel mutation in transmembrane region of glycoprotein IX affects platelet surface expressions of glycoprotein GP-Ib-IX complex and causes Bernard Soulier syndrome." Xu L., Liu L., Zhang D., Sun G., Wang P., Sun N., Hu Q., Li X., Cao F., Peng B., Yu S. Submitted (2009-10) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-181