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ELISA Kit for Human Piezo-type mechanosensitive ion channel component 1

SKU : BHE13809655

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E3227h
Alternative Names	Membrane protein induced by beta-amyloid treatment ; Mib ; Protein FAM38A ; FAM38A ; KIAA0233
Categories	Elisa
Function	Component of mechanosensitive channel required for the mechanosensitive currents. Plays a key role in epithelial cell adhesion by maintaining integrin activation through R-Ras recruitment to the ER, most probably in its activated state, and subsequent stimulation of calpain signaling.
Specificity	Natural and recombinant Human Piezo-type mechanosensitive ion channel component 1
Subcellular Location	Endoplasmic reticulum membrane Multi-pass membrane protein Endoplasmic reticulum-Golgi intermediate compartment membrane Cell membrane Multi-pass membrane protein
Detection Range	0.156-10ng/ml
Entryname	PIEZ1_HUMAN
Method Type	Competitive
Platform	PF12166
Protein Name	Piezo-type mechanosensitive ion channel component 1
Sensitivity	0.078ng/mL
Sequence	50: MEPHVLGAVL ; YWLLLPCALL ; AACLLRFSGL ; SLVYLLFLLL ; LPWFPGPTRC ; 100: GLQGHTGRLL ; RALLGLSLLF ; LVAHLALQIC ; LHIVPRLDQL ; LGPSCSRWET ; 150: LSRHIGVTRL ; DLKDIPNAIR ; LVAPDLGILV ; VSSVCLGICG ; RLARNTRQSP ; 200: HPRELDDDER ; DVDASPTAGL ; QEAATLAPTR ; RSRLAARFRV ; TAHWLLVAAG ; 250: RVLAVTLLAL ; AGIAHPSALS ; SVYLLLFLAL ; CTWWACHFPI ; STRGFSRLCV ; 300: AVGCFGAGHL ; ICLYCYQMPL ; AQALLPPAGI ; WARVLGLKDF ; VGPTNCSSPH ; 350: ALVLNTGLDW ; PVYASPGVLL ; LLCYATASLR ; KLRAYRPSGQ ; RKEAAKGYEA ; 400: RELELAELDQ ; WPQERESDQH ; VVPTAPDTEA ; DNCIVHELTG ; QSSVLRRPVR ; 450: PKRAEPREAS ; PLHSLGHLIM ; DQSYVCALIA ; MMVWSITYHS ; WLTFVLLLWA ; 500: CLIWTVRSRH ; QLAMLCSPCI ; LLYGMTLCCL ; RYVWAMDLRP ; ELPTTLGPVS ; 550: LRQLGLEHTR ; YPCLDLGAML ; LYTLTFWLLL ; RQFVKEKLLK ; WAESPAALTE ; 600: VTVADTEPTR ; TQTLLQSLGE ; LVKGVYAKYW ; IYVCAGMFIV ; VSFAGRLVVY ; 650: KIVYMFLFLL ; CLTLFQVYYS ; LWRKLLKAFW ; WLVVAYTMLV ; LIAVYTFQFQ ; 700: DFPAYWRNLT ; GFTDEQLGDL ; GLEQFSVSEL ; FSSILVPGFF ; LLACILQLHY ; 750: FHRPFMQLTD ; MEHVSLPGTR ; LPRWAHRQDA ; VSGTPLLREE ; QQEHQQQQQE ; 800: EEEEEEDSRD ; EGLGVATPHQ ; ATQVPEGAAK ; WGLVAERLLE ; LAAGFSDVLS ; 850: RVQVFLRRLL ; ELHVFKLVAL ; YTVWVALKEV ; SVMNLLLVVL ; WAFALPYPRF ; 900: RPMASCLSTV ; WTCVIIVCKM ; LYQLKVVNPQ ; EYSSNCTEPF ; PNSTNLLPTE ; 950: ISQSLLYRGP ; VDPANWFGVR ; KGFPNLGYIQ ; NHLQVLLLLV ; FEAIVYRRQE ; 1000: HYRRQHQLAP ; LPAQAVFASG ; TRQQLDQDLL ; GCLKYFINFF ; FYKFGLEICF ; 1050: LMAVNVIGQR ; MNFLVTLHGC ; WLVAILTRRH ; RQAIARLWPN ; YCLFLALFLL ; 1100: YQYLLCLGMP ; PALCIDYPWR ; WSRAVPMNSA ; LIKWLYLPDF ; FRAPNSTNLI ; 1150: SDFLLLLCAS ; QQWQVFSAER ; TEEWQRMAGV ; NTDRLEPLRG ; EPNPVPNFIH ; 1200: CRSYLDMLKV ; AVFRYLFWLV ; LVVVFVTGAT ; RISIFGLGYL ; LACFYLLLFG ; 1250: TALLQRDTRA ; RLVLWDCLIL ; YNVTVIISKN ; MLSLLACVFV ; EQMQTGFCWV ; 1300: IQLFSLVCTV ; KGYYDPKEMM ; DRDQDCLLPV ; EEAGIIWDSV ; CFFFLLLQRR ; 1350: VFLSHYYLHV ; RADLQATALL ; ASRGFALYNA ; ANLKSIDFHR ; RIEEKSLAQL ; 1400: KRQMERIRAK ; QEKHRQGRVD ; RSRPQDTLGP ; KDPGLEPGPD ; SPGGSSPPRR ; 1450: QWWRPWLDHA ; TVIHSGDYFL ; FESDSEEEEE ; AVPEDPRPSA ; QSAFQLAYQA ; 1500: WVTNAQAVLR ; RRQQEQEQAR ; QEQAGQLPTG ; GGPSQEVEPA ; EGPEEAAAGR ; 1550: SHVVQRVLST ; AQFLWMLGQA ; LVDELTRWLQ ; EFTRHHGTMS ; DVLRAERYLL ; 1600: TQELLQGGEV ; HRGVLDQLYT ; SQAEATLPGP ; TEAPNAPSTV ; SSGLGAEEPL ; 1650: SSMTDDMGSP ; LSTGYHTRSG ; SEEAVTDPGE ; REAGASLYQG ; LMRTASELLL ; 1700: DRRLRIPELE ; EAELFAEGQG ; RALRLLRAVY ; QCVAAHSELL ; CYFIIILNHM ; 1750: VTASAGSLVL ; PVLVFLWAML ; SIPRPSKRFW ; MTAIVFTEIA ; VVVKYLFQFG ; 1800: FFPWNSHVVL ; RRYENKPYFP ; PRILGLEKTD ; GYIKYDLVQL ; MALFFHRSQL ; 1850: LCYGLWDHEE ; DSPSKEHDKS ; GEEEQGAEEG ; PGVPAATTED ; HIQVEARVGP ; 1900: TDGTPEPQVE ; LRPRDTRRIS ; LRFRRRKKEG ; PARKGAAAIE ; AEDREEEEGE ; 1950: EEKEAPTGRE ; KRPSRSGGRV ; RAAGRRLQGF ; CLSLAQGTYR ; PLRRFFHDIL ; 2000: HTKYRAATDV ; YALMFLADVV ; DFIIIIFGFW ; AFGKHSAATD ; ITSSLSDDQV ; 2050: PEAFLVMLLI ; QFSTMVVDRA ; LYLRKTVLGK ; LAFQVALVLA ; IHLWMFFILP ; 2100: AVTERMFNQN ; VVAQLWYFVK ; CIYFALSAYQ ; IRCGYPTRIL ; GNFLTKKYNH ; 2150: LNLFLFQGFR ; LVPFLVELRA ; VMDWVWTDTT ; LSLSSWMCVE ; DIYANIFIIK ; 2200: CSRETEKKYP ; QPKGQKKKKI ; VKYGMGGLII ; LFLIAIIWFP ; LLFMSLVRSV ; 2250: VGVVNQPIDV ; TVTLKLGGYE ; PLFTMSAQQP ; SIIPFTAQAY ; EELSRQFDPQ ; 2300: PLAMQFISQY ; SPEDIVTAQI ; EGSSGALWRI ; SPPSRAQMKR ; ELYNGTADIT ; 2350: LRFTWNFQRD ; LAKGGTVEYA ; NEKHMLALAP ; NSTARRQLAS ; LLEGTSDQSV ; 2400: VIPNLFPKYI ; RAPNGPEANP ; VKQLQPNEEA ; DYLGVRIQLR ; REQGAGATGF ; 2450: LEWWVIELQE ; CRTDCNLLPM ; VIFSDKVSPP ; SLGFLAGYGI ; MGLYVSIVLV ; 2500: IGKFVRGFFS ; EISHSIMFEE ; LPCVDRILKL ; CQDIFLVRET ; RELELEEELY ; 2521: AKLIFLYRSP ; ETMIKWTREK ; E
Sequence Length	2521
String	Q92508

Uniprot	Q92508
Gene Name	PIEZO1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:9780
Unigene	Hs.377001

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