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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Phosphatidylinositol phosphatase PTPRQ

SKU : BHE13809551

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E10382h
Alternative Names	Receptor-type tyrosine-protein phosphatase Q ; PTP-RQ ; 3.1.3.48
Categories	Elisa
Function	Phosphatidylinositol phosphatase required for auditory function. May act by regulating the level of phosphatidylinositol 4,5-bisphosphate (PIP2) level in the basal region of hair bundles. Can dephosphorylate a broad range of phosphatidylinositol phosphates, including phosphatidylinositol 3,4,5-trisphosphate and most phosphatidylinositol monophosphates and diphosphates. Phosphate can be hydrolyzed from the D3 and D5 positions in the inositol ring. Has low tyrosine-protein phosphatase activity; however, the relevance of such activity in vivo is unclear. Plays an important role in adipogenesis of mesenchymal stem cells (MSCs). Regulates the phosphorylation state of AKT1 by suppressing the phosphatidylinositol 3,4,5-trisphosphate (PIP3) level in MSCs and preadipocyte cells.
Specificity	Natural and recombinant Human Phosphatidylinositol phosphatase PTPRQ
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	0.78-50ng/mL
Entryname	PTPRQ_HUMAN
Method Type	Competitive
Platform	PF00041
Protein Name	Phosphatidylinositol phosphatase PTPRQ
Sensitivity	0.23ng/mL
Sequence	50: MKKVPIKPEQ ; PEKLRAFNIS ; THSFSLHWSL ; PSGHVERYQV ; DLVPDSGFVT ; 100: IRDLGGGEYQ ; VDVSNVVPGT ; RYDITISSIS ; TTYTSPVTRI ; VTTNVTKPGP ; 150: PVFLAGERVG ; SAGILLSWNT ; PPNPNGRIIS ; YIVKYKEVCP ; WMQTVYTQVR ; 200: SKPDSLEVLL ; TNLNPGTTYE ; IKVAAENSAG ; IGVFSDPFLF ; QTAESAPGKV ; 250: VNLTVEAYNA ; SAVKLIWYLP ; RQPNGKITSF ; KISVKHARSG ; IVVKDVSIRV ; 300: EDILTGKLPE ; CNENSESFLW ; STASPSPTLG ; RVTPPSRTTH ; SSSTLTQNEI ; 350: SSVWKEPISF ; VVTHLRPYTT ; YLFEVSAVTT ; EAGYIDSTIV ; RTPESVPEGP ; 400: PQNCVTGNIT ; GKSFSILWDP ; PTIVTGKFSY ; RVELYGPSGR ; ILDNSTKDLK ; 450: FAFTNLTPFT ; MYDVYIAAET ; SAGTGPKSNI ; SVFTPPDVPG ; AVFDLQLAEV ; 500: ESTQVRITWK ; KPRQPNGIIN ; QYRVKVLVPE ; TGIILENTLL ; TGNNEYINDP ; 550: MAPEIVNIVE ; PMVGLYEGSA ; EMSSDLHSLA ; TFIYNSHPDK ; NFPARNRAED ; 600: QTSPVVTTRN ; QYITDIAAEQ ; LSYVIRRLVP ; FTEHMISVSA ; FTIMGEGPPT ; 650: VLSVRTRQQV ; PSSIKIINYK ; NISSSSILLY ; WDPPEYPNGK ; ITHYTIYAME ; 700: LDTNRAFQIT ; TIDNSFLITG ; LKKYTKYKMR ; VAASTHVGES ; SLSEENDIFV ; 750: RTSEDEPESS ; PQDVEVIDVT ; ADEIRLKWSP ; PEKPNGIIIA ; YEVLYKNIDT ; 800: LYMKNTSTTD ; IILRNLRPHT ; LYNISVRSYT ; RFGHGNQVSS ; LLSVRTSETV ; 850: PDSAPENITY ; KNISSGEIEL ; SFLPPSSPNG ; IIKKYTIYLK ; RSNGNEERTI ; 900: NTTSLTQNIK ; VLKKYTQYII ; EVSASTLKGE ; GVRSAPISIL ; TEEDAPDSPP ; 950: QDFSVKQLSG ; VTVKLSWQPP ; LEPNGIILYY ; TVYVWNRSSL ; KTINVTETSL ; 1000: ELSDLDYNVE ; YSAYVTASTR ; FGDGKTRSNI ; ISFQTPEGAP ; SDPPKDVYYA ; 1050: NLSSSSIILF ; WTPPSKPNGI ; IQYYSVYYRN ; TSGTFMQNFT ; LHEVTNDFDN ; 1100: MTVSTIIDKL ; TIFSYYTFWL ; TASTSVGNGN ; KSSDIIEVYT ; DQDIPEGFVG ; 1150: NLTYESISST ; AINVSWVPPA ; QPNGLVFYYV ; SLILQQTPRH ; VRPPLVTYER ; 1200: SIYFDNLEKY ; TDYILKITPS ; TEKGFSDTYT ; AQLYIKTEED ; VPETSPIINT ; 1250: FKNLSSTSVL ; LSWDPPVKPN ; GAIISYDLTL ; QGPNENYSFI ; TSDNYIILEE ; 1300: LSPFTLYSFF ; AAARTRKGLG ; PSSILFFYTD ; ESVPLAPPQN ; LTLINCTSDF ; 1350: VWLKWSPSPL ; PGGIVKVYSF ; KIHEHETDTI ; YYKNISGFKT ; EAKLVGLEPV ; 1400: STYSIRVSAF ; TKVGNGNQFS ; NVVKFTTQES ; VPDVVQNMQC ; MATSWQSVLV ; 1450: KWDPPKKANG ; IITQYMVTVE ; RNSTKVSPQD ; HMYTFIKLLA ; NTSYVFKVRA ; 1500: STSAGEGDES ; TCHVSTLPET ; VPSVPTNIAF ; SDVQSTSATL ; TWIRPDTILG ; 1550: YFQNYKITTQ ; LRAQKCKEWE ; SEECVEYQKI ; QYLYEAHLTE ; ETVYGLKKFR ; 1600: WYRFQVAAST ; NAGYGNASNW ; ISTKTLPGPP ; DGPPENVHVV ; ATSPFSISIS ; 1650: WSEPAVITGP ; TCYLIDVKSV ; DNDEFNISFI ; KSNEENKTIE ; IKDLEIFTRY ; 1700: SVVITAFTGN ; ISAAYVEGKS ; SAEMIVTTLE ; SAPKDPPNNM ; TFQKIPDEVT ; 1750: KFQLTFLPPS ; QPNGNIQVYQ ; ALVYREDDPT ; AVQIHNLSII ; QKTNTFVIAM ; 1800: LEGLKGGHTY ; NISVYAVNSA ; GAGPKVPMRI ; TMDIKAPARP ; KTKPTPIYDA ; 1850: TGKLLVTSTT ; ITIRMPICYY ; SDDHGPIKNV ; QVLVTETGAQ ; HDGNVTKWYD ; 1900: AYFNKARPYF ; TNEGFPNPPC ; TEGKTKFSGN ; EEIYIIGADN ; ACMIPGNEDK ; 1950: ICNGPLKPKK ; QYLFKFRATN ; IMGQFTDSDY ; SDPVKTLGEG ; LSERTVEIIL ; 2000: SVTLCILSII ; LLGTAIFAFA ; RIRQKQKEGG ; TYSPQDAEII ; DTKLKLDQLI ; 2050: TVADLELKDE ; RLTRPISKKS ; FLQHVEELCT ; NNNLKFQEEF ; SELPKFLQDL ; 2100: SSTDADLPWN ; RAKNRFPNIK ; PYNNNRVKLI ; ADASVPGSDY ; INASYISGYL ; 2150: CPNEFIATQG ; PLPGTVGDFW ; RMVWETRAKT ; LVMLTQCFEK ; GRIRCHQYWP ; 2200: EDNKPVTVFG ; DIVITKLMED ; VQIDWTIRDL ; KIERHGDCMT ; VRQCNFTAWP ; 2250: EHGVPENSAP ; LIHFVKLVRA ; SRAHDTTPMI ; VHCSAGVGRT ; GVFIALDHLT ; 2300: QHINDHDFVD ; IYGLVAELRS ; ERMCMVQNLA ; QYIFLHQCIL ; DLLSNKGSNQ ; 2332: PICFVNYSAL ; QKMDSLDAME ; GDVELEWEET ; TM
Sequence Length	2332
String	Q9UMZ3

Uniprot	Q9UMZ3
Gene Name	PTPRQ
Immunogen Species	Homo Sapiens (Human)
Unigene	Hs.539284

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