JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Human P-selectin glycoprotein ligand 1

SKU : BHE13810608

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E9106h
Alternative Names	Selectin P ligand ; CD162
Categories	Elisa
Function	A SLe(x)-type glycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. PSGL1 is critical for the initial leukocyte capture.
Specificity	Natural and recombinant Human P-selectin glycoprotein ligand 1
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	0.625-40ng/mL
Entryname	SELPL_HUMAN
Method Type	Sandwich
Protein Name	P-selectin glycoprotein ligand 1
Sensitivity	0.319ng/mL
Sequence	50: MPLQLLLLLI ; LLGPGNSLQL ; WDTWADEAEK ; ALGPLLARDR ; RQATEYEYLD ; 100: YDFLPETEPP ; EMLRNSTDTT ; PLTGPGTPES ; TTVEPAARRS ; TGLDAGGAVT ; 150: ELTTELANMG ; NLSTDSAAME ; IQTTQPAATE ; AQTTQPVPTE ; AQTTPLAATE ; 200: AQTTRLTATE ; AQTTPLAATE ; AQTTPPAATE ; AQTTQPTGLE ; AQTTAPAAME ; 250: AQTTAPAAME ; AQTTPPAAME ; AQTTQTTAME ; AQTTAPEATE ; AQTTQPTATE ; 300: AQTTPLAAME ; ALSTEPSATE ; ALSMEPTTKR ; GLFIPFSVSS ; VTHKGIPMAA ; 350: SNLSVNYPVG ; APDHISVKQC ; LLAILILALV ; ATIFFVCTVV ; LAVRLSRKGH ; 400: MYPVRNYSPT ; EMVCISSLLP ; DGGEGPSATA ; NGGLSKAKSP ; GLTPEPREDR ; 412: EGDDLTLHSF ; LP
Sequence Length	412
String	Q14242
Sub Unit	Homodimer; disulfide-linked. Interaction with P-, E- and L-selectins, through their lectin/EGF domains, is required for promoting recruitment and rolling of leukocytes. These interactions require sialyl Lewis X glycan modification but there is a differing dependence for tyrosine sulfations. Sulfation on Tyr-51 of PSGL1 is most important for high affinity L-selectin/SELL binding while P-selectin/SELP requires sulfation on Tyr-48. E-selectin/SELE binds with much lower affinity and requires the sLe(x) epitope, but apparantly not tyrosine sulfation. Dimerization appears not to be required for P-selectin/SELP binding. Interacts with SNX20.

Uniprot	Q14242
Gene Name	SELPLG
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:6404
Unigene	Hs.591014

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13810608	E9106h	96T	$736		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.