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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Nuclear receptor coactivator 3

SKU : BHE13806924

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E11290h
Alternative Names	ACTR ; Amplified in breast cancer 1 protein ; AIB-1 ; CBP-interacting protein ; pCIP ; Class E basic helix-loop-helix protein 42 ; bHLHe42 ; Receptor-associated coactivator 3 ; RAC-3 ; Steroid receptor coactivator protein 3 ; SRC-3 ; Thyroid hormone receptor activator molecule 1 ; TRAM-1 ; AIB1 ; BHLHE42 ; RAC3 ; TRAM1
Categories	Elisa
Function	Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit. Interacts with PSMB9.
Specificity	Natural and recombinant Human Nuclear receptor coactivator 3
Subcellular Location	Cytoplasm Nucleus Mainly cytoplasmic and weakly nuclear. Upon TNF activation and subsequent phosphorylation, it translocates from the cytoplasm to the nucleus.
Detection Range	0.312-20ng/mL
Entryname	NCOA3_HUMAN
Method Type	Sandwich
Platform	PF07469
Protein Name	Nuclear receptor coactivator 3
Sensitivity	0.099ng/mL
Sequence	50: MSGLGENLDP ; LASDSRKRKL ; PCDTPGQGLT ; CSGEKRRREQ ; ESKYIEELAE ; 100: LISANLSDID ; NFNVKPDKCA ; ILKETVRQIR ; QIKEQGKTIS ; NDDDVQKADV ; 150: SSTGQGVIDK ; DSLGPLLLQA ; LDGFLFVVNR ; DGNIVFVSEN ; VTQYLQYKQE ; 200: DLVNTSVYNI ; LHEEDRKDFL ; KNLPKSTVNG ; VSWTNETQRQ ; KSHTFNCRML ; 250: MKTPHDILED ; INASPEMRQR ; YETMQCFALS ; QPRAMMEEGE ; DLQSCMICVA ; 300: RRITTGERTF ; PSNPESFITR ; HDLSGKVVNI ; DTNSLRSSMR ; PGFEDIIRRC ; 350: IQRFFSLNDG ; QSWSQKRHYQ ; EAYLNGHAET ; PVYRFSLADG ; TIVTAQTKSK ; 400: LFRNPVTNDR ; HGFVSTHFLQ ; REQNGYRPNP ; NPVGQGIRPP ; MAGCNSSVGG ; 450: MSMSPNQGLQ ; MPSSRAYGLA ; DPSTTGQMSG ; ARYGGSSNIA ; SLTPGPGMQS ; 500: PSSYQNNNYG ; LNMSSPPHGS ; PGLAPNQQNI ; MISPRNRGSP ; KIASHQFSPV ; 550: AGVHSPMASS ; GNTGNHSFSS ; SSLSALQAIS ; EGVGTSLLST ; LSSPGPKLDN ; 600: SPNMNITQPS ; KVSNQDSKSP ; LGFYCDQNPV ; ESSMCQSNSR ; DHLSDKESKE ; 650: SSVEGAENQR ; GPLESKGHKK ; LLQLLTCSSD ; DRGHSSLTNS ; PLDSSCKESS ; 700: VSVTSPSGVS ; SSTSGGVSST ; SNMHGSLLQE ; KHRILHKLLQ ; NGNSPAEVAK ; 750: ITAEATGKDT ; SSITSCGDGN ; VVKQEQLSPK ; KKENNALLRY ; LLDRDDPSDA ; 800: LSKELQPQVE ; GVDNKMSQCT ; SSTIPSSSQE ; KDPKIKTETS ; EEGSGDLDNL ; 850: DAILGDLTSS ; DFYNNSISSN ; GSHLGTKQQV ; FQGTNSLGLK ; SSQSVQSIRP ; 900: PYNRAVSLDS ; PVSVGSSPPV ; KNISAFPMLP ; KQPMLGGNPR ; MMDSQENYGS ; 950: SMGGPNRNVT ; VTQTPSSGDW ; GLPNSKAGRM ; EPMNSNSMGR ; PGGDYNTSLP ; 1000: RPALGGSIPT ; LPLRSNSIPG ; ARPVLQQQQQ ; MLQMRPGEIP ; MGMGANPYGQ ; 1050: AAASNQLGSW ; PDGMLSMEQV ; SHGTQNRPLL ; RNSLDDLVGP ; PSNLEGQSDE ; 1100: RALLDQLHTL ; LSNTDATGLE ; EIDRALGIPE ; LVNQGQALEP ; KQDAFQGQEA ; 1150: AVMMDQKAGL ; YGQTYPAQGP ; PMQGGFHLQG ; QSPSFNSMMN ; QMNQQGNFPL ; 1200: QGMHPRANIM ; RPRTNTPKQL ; RMQLQQRLQG ; QQFLNQSRQA ; LELKMENPTA ; 1250: GGAAVMRPMM ; QPQVSSQQGF ; LNAQMVAQRS ; RELLSHHFRQ ; QRVAMMMQQQ ; 1300: QQQQQQQQQQ ; QQQQQQQQQQ ; QQQQQQTQAF ; SPPPNVTASP ; SMDGLLAGPT ; 1350: MPQAPPQQFP ; YQPNYGMGQQ ; PDPAFGRVSS ; PPNAMMSSRM ; GPSQNPMMQH ; 1400: PQAASIYQSS ; EMKGWPSGNL ; ARNSSFSQQQ ; FAHQGNPAVY ; SMVHMNGSSG ; 1424: HMGQMNMNPM ; PMSGMPMGPD ; QKYC
Sequence Length	1424
String	Q9Y6Q9
Sub Unit	Interacts with CARM1 (By similarity). Present in a complex containing NCOA2, IKKA, IKKB, IKBKG and the histone acetyltransferase protein CREBBP. Interacts with CASP8AP2, NR3C1 and PCAF. Interacts with ATAD2 and this interaction is enhanced by estradiol.

Uniprot	Q9Y6Q9
Gene Name	NCOA3
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:8202
Unigene	Hs.592142

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806924	E11290h	96T	$736		Add to Cart

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