ELISA Kit for Human Mps one binder kinase activator-like 1A

Mfr.No.	E2913h
Alternative Names	Mob1 homolog 1A ; Mob1A ; Mob1B ; Protein Mob4A ; MOB4A
Categories	Elisa
Function	Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38L.
Specificity	Natural and recombinant Human Mps one binder kinase activator-like 1A
Subcellular Location	Cytoplasm Nucleus
Entryname	MOL1A_HUMAN
Platform	PF03637
Protein Name	Mps one binder kinase activator-like 1A
Sequence	50: MSFLFGSRSS ; KTFKPKKNIP ; EGSHQYELLK ; HAEATLGSGN ; LRMAVMLPEG ; 100: EDLNEWVAVN ; TVDFFNQINM ; LYGTITDFCT ; EESCPVMSAG ; PKYEYHWADG ; 150: TNIKKPIKCS ; APKYIDYLMT ; WVQDQLDDET ; LFPSKIGVPF ; PKNFMSVAKT ; 200: ILKRLFRVYA ; HIYHQHFDPV ; IQLQEEAHLN ; TSFKHFIFFV ; QEFNLIDRRE ; 216: LAPLQELIEK ; LTSKDR
Sequence Length	216
String	Q7L9L4
Sub Unit	Binds STK38L. Interacts with LATS1 and LATS2.

Reference

Have you used this product?

SKU	Supplier No.	Size	Your price	Quantity
BHE13806562	E2913h	96T	$736		Add to Cart