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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Mitogen-activated protein kinase 1

SKU : BHE13812193

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1206h
Alternative Names	ERT1 ; Extracellular signal-regulated kinase 2 ; ERK-2 ; MAP kinase isoform p42 ; p42-MAPK ; Mitogen-activated protein kinase 2 ; MAP kinase 2 ; ERK2 ; PRKM1 ; PRKM2
Categories	Elisa
Function	Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity.
Specificity	Natural and recombinant Human Mitogen-activated protein kinase 1
Subcellular Location	Nucleus Cytoplasm cytoskeleton centrosome
Detection Range	0.156-10ng/mL
Entryname	MK01_HUMAN
Method Type	Sandwich
Platform	PF00069
Protein Name	Mitogen-activated protein kinase 1
Sensitivity	0.089ng/mL
Sequence	50: MAAAAAAGAG ; PEMVRGQVFD ; VGPRYTNLSY ; IGEGAYGMVC ; SAYDNVNKVR ; 100: VAIKKISPFE ; HQTYCQRTLR ; EIKILLRFRH ; ENIIGINDII ; RAPTIEQMKD ; 150: VYIVQDLMET ; DLYKLLKTQH ; LSNDHICYFL ; YQILRGLKYI ; HSANVLHRDL ; 200: KPSNLLLNTT ; CDLKICDFGL ; ARVADPDHDH ; TGFLTEYVAT ; RWYRAPEIML ; 250: NSKGYTKSID ; IWSVGCILAE ; MLSNRPIFPG ; KHYLDQLNHI ; LGILGSPSQE ; 300: DLNCIINLKA ; RNYLLSLPHK ; NKVPWNRLFP ; NADSKALDLL ; DKMLTFNPHK ; 350: RIEVEQALAH ; PYLEQYYDPS ; DEPIAEAPFK ; FDMELDDLPK ; EKLKELIFEE ; 360: TARFQPGYRS ;
Sequence Length	360
String	P28482
Sub Unit	Interacts with MORG1 (By similarity). Binds to HIV-1 Nef through its SH3 domain. This interaction inhibits its tyrosine-kinase activity. Interacts with its substrates HSF4 and ARHGEF2. Interacts (phosphorylated form) with CAV2 ('Tyr-19'-phosphorylated form); the interaction, promoted by insulin, leads to nuclear location and MAPK1 activation (By similarity). Interacts with NISCH. Interacts with ARRB2. Interacts with ADAM15. Interacts with isoform 1 of NEK2.

Uniprot	P28482
Gene Name	MAPK1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:5594
Unigene	Hs.431850

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SKU	Supplier No.	Size	Your price	Quantity
BHE13812193	E1206h	96T	$736		Add to Cart

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