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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Mineralocorticoid receptor

SKU : BHE13807142

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0158h
Alternative Names	Nuclear receptor subfamily 3 group C member 2 ; MCR ; MLR
Categories	Elisa
Function	Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
Specificity	Natural and recombinant Human Mineralocorticoid receptor
Subcellular Location	Cytoplasm Nucleus Endoplasmic reticulum membrane Peripheral membrane protein Cytoplasmic and nuclear in the absence of ligand; nuclear after ligand-binding. When bound to HSD11B2, it is found associated with the endoplasmic reticulum membrane.
Detection Range	0.156-10ng/mL
Entryname	MCR_HUMAN
Method Type	Sandwich
Platform	PF00104
Protein Name	Mineralocorticoid receptor
Sensitivity	0.081ng/mL
Sequence	50: METKGYHSLP ; EGLDMERRWG ; QVSQAVERSS ; LGPTERTDEN ; NYMEIVNVSC ; 100: VSGAIPNNST ; QGSSKEKQEL ; LPCLQQDNNR ; PGILTSDIKT ; ELESKELSAT ; 150: VAESMGLYMD ; SVRDADYSYE ; QQNQQGSMSP ; AKIYQNVEQL ; VKFYKGNGHR ; 200: PSTLSCVNTP ; LRSFMSDSGS ; SVNGGVMRAI ; VKSPIMCHEK ; SPSVCSPLNM ; 250: TSSVCSPAGI ; NSVSSTTASF ; GSFPVHSPIT ; QGTPLTCSPN ; AENRGSRSHS ; 300: PAHASNVGSP ; LSSPLSSMKS ; SISSPPSHCS ; VKSPVSSPNN ; VTLRSSVSSP ; 350: ANINNSRCSV ; SSPSNTNNRS ; TLSSPAASTV ; GSICSPVNNA ; FSYTASGTSA ; 400: GSSTLRDVVP ; SPDTQEKGAQ ; EVPFPKTEEV ; ESAISNGVTG ; QLNIVQYIKP ; 450: EPDGAFSSSC ; LGGNSKINSD ; SSFSVPIKQE ; STKHSCSGTS ; FKGNPTVNPF ; 500: PFMDGSYFSF ; MDDKDYYSLS ; GILGPPVPGF ; DGNCEGSGFP ; VGIKQEPDDG ; 550: SYYPEASIPS ; SAIVGVNSGG ; QSFHYRIGAQ ; GTISLSRSAR ; DQSFQHLSSF ; 600: PPVNTLVESW ; KSHGDLSSRR ; SDGYPVLEYI ; PENVSSSTLR ; SVSTGSSRPS ; 650: KICLVCGDEA ; SGCHYGVVTC ; GSCKVFFKRA ; VEGQHNYLCA ; GRNDCIIDKI ; 700: RRKNCPACRL ; QKCLQAGMNL ; GARKSKKLGK ; LKGIHEEQPQ ; QQQPPPPPPP ; 750: PQSPEEGTTY ; IAPAKEPSVN ; TALVPQLSTI ; SRALTPSPVM ; VLENIEPEIV ; 800: YAGYDSSKPD ; TAENLLSTLN ; RLAGKQMIQV ; VKWAKVLPGF ; KNLPLEDQIT ; 850: LIQYSWMCLS ; SFALSWRSYK ; HTNSQFLYFA ; PDLVFNEEKM ; HQSAMYELCQ ; 900: GMHQISLQFV ; RLQLTFEEYT ; IMKVLLLLST ; IPKDGLKSQA ; AFEEMRTNYI ; 950: KELRKMVTKC ; PNNSGQSWQR ; FYQLTKLLDS ; MHDLVSDLLE ; FCFYTFRESH ; 984: ALKVEFPAML ; VEIISDQLPK ; VESGNAKPLY ; FHRK
Sequence Length	984
String	P08235
Sub Unit	Heteromultimeric cytoplasmic complex with HSP90, HSP70, and FKBP4, in the absence of ligand. After ligand binding, it translocates to the nucleus and binds to DNA as a homodimer and as a heterodimer with NR3C1. May interact with HSD11B2 in the absence of ligand. Binds the coactivators NCOA1, NCOA2, TIF1 and NRIP1.

Uniprot	P08235
Gene Name	NR3C2
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:4306
Unigene	Hs.163924

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SKU	Supplier No.	Size	Your price	Quantity
BHE13807142	E0158h	96T	$736		Add to Cart

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