Receptor for glutamate. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current.
Specificity
Natural and recombinant Human Metabotropic glutamate receptor 5
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);FUNCTION;SUBCELLULAR LOCATION
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 860-952 (ISOFORM 2)
"Metabotropic glutamate receptor MGluR5 complexed with glutamate." Structural genomics consortium (SGC) Submitted (2011-07) to the PDB data bank
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.44 ANGSTROMS) OF 18-505 IN COMPLEX WITH GLUTAMATE;GLYCOSYLATION AT ASN-445;DISULFIDE BONDS
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) OF 569-836 IN COMPLEX WITH ALLOSTERIC EFFECTOR;FUNCTION;SUBCELLULAR LOCATION;TOPOLOGY;DISULFIDE BONDS;MUTAGENESIS OF SER-613; SER-614; LYS-665 AND GLU-770
Reviews of ELISA Kit for Human Metabotropic glutamate receptor 5