ME20-M ; ME20M ; Melanocyte protein Pmel 17 ; Melanocytes lineage-specific antigen GP100 ; Melanoma-associated ME20 antigen ; P1 ; P100 ; Premelanosome protein ; Silver locus protein homolog ; D12S53E ; PMEL17 ; SILV
Categories
Elisa
Function
Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.
Specificity
Natural and recombinant Human Melanocyte protein PMEL