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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Meiotic recombination protein REC8 homolog

SKU : BHE13809979

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E4955h
Alternative Names	Cohesin Rec8p ; REC8L1
Categories	Elisa
Function	Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II.
Specificity	Natural and recombinant Human Meiotic recombination protein REC8 homolog
Subcellular Location	Nucleus Chromosome In meiotic chromosomes, localized along axial elements in prophase from the leptotene to diplotene stages. At later prophase stages, diakinesis and metaphase I, localized along interstitial axes of chromosomes including both centromere and arm regions. No longer detected in arm regions in anaphase I but persists on centromere regions until metaphase II.
Detection Range	0.78-50ng/ml
Entryname	REC8_HUMAN
Method Type	Competitive
Platform	PF04824
Protein Name	Meiotic recombination protein REC8 homolog
Sensitivity	0.39ng/mL
Sequence	50: MFYYPNVLQR ; HTGCFATIWL ; AATRGSRLVK ; REYLRVNVVK ; TCEEILNYVL ; 100: VRVQPPQPGL ; PRPRFSLYLS ; AQLQIGVIRV ; YSQQCQYLVE ; DIQHILERLH ; 150: RAQLQIRIDM ; ETELPSLLLP ; NHLAMMETLE ; DAPDPFFGMM ; SVDPRLPSPF ; 200: DIPQIRHLLE ; AAIPERVEEI ; PPEVPTEPRE ; PERIPVTVLP ; PEAITILEAE ; 250: PIRMLEIEGE ; RELPEVSRRE ; LDLLIAEEEE ; AILLEIPRLP ; PPAPAEVEGI ; 300: GEALGPEELR ; LTGWEPGALL ; MEVTPPEELR ; LPAPPSPERR ; PPVPPPPRRR ; 350: RRRRLLFWDK ; ETQISPEKFQ ; EQLQTRAHCW ; ECPMVQPPER ; TIRGPAELFR ; 400: TPTLSGWLPP ; ELLGLWTHCA ; QPPPKALRRE ; LPEEAAAEEE ; RRKIEVPSEI ; 450: EVPREALEPS ; VPLMVSLEIS ; LEAAEEEKSR ; ISLIPPEERW ; AWPEVEAPEA ; 500: PALPVVPELP ; EVPMEMPLVL ; PPELELLSLE ; AVHRAVALEL ; QANREPDFSS ; 547: LVSPLSPRRM ; AARVFYLLLV ; LSAQQILHVK ; QEKPYGRLLI ; QPGPRFH
Sequence Length	547
String	O95072
Sub Unit	Interacts (phosphorylated and unphosphorylated form) with SMC3. Interacts with SYCP3. Interacts (phosphorylated and unphosphorylated form) with SMC1B. Does not interact with SMC1A. Interacts with RAD51.

Uniprot	O95072
Gene Name	REC8
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:9985
Unigene	Hs.419259

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809979	E4955h	96T	$736		Add to Cart

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