Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy.
Specificity
Natural and recombinant Human Macrophage colony-stimulating factor 1
Subcellular Location
Processed macrophage colony-stimulating factor 1 Secreted extracellular space