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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Lysine--tRNA ligase

SKU : BHE13812246

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0187h
Alternative Names	Lysyl-tRNA synthetase ; LysRS ; KIAA0070
Categories	Elisa
Function	Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of diadenosine oligophosphate (Ap4A), a signaling molecule involved in the activation of MITF transcriptional activity. Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA(3)(Lys), the primer for reverse transcription initiation.
Specificity	Natural and recombinant Human Lysine--tRNA ligase
Subcellular Location	Isoform Mitochondrial Mitochondrion
Detection Range	0.312-20ng/mL
Entryname	SYK_HUMAN
Method Type	Sandwich
Platform	PF00152
Protein Name	Lysine--tRNA ligase
Sensitivity	0.156ng/mL
Sequence	50: MAAVQAAEVK ; VDGSEPKLSK ; NELKRRLKAE ; KKVAEKEAKQ ; KELSEKQLSQ ; 100: ATAAATNHTT ; DNGVGPEEES ; VDPNQYYKIR ; SQAIHQLKVN ; GEDPYPHKFH ; 150: VDISLTDFIQ ; KYSHLQPGDH ; LTDITLKVAG ; RIHAKRASGG ; KLIFYDLRGE ; 200: GVKLQVMANS ; RNYKSEEEFI ; HINNKLRRGD ; IIGVQGNPGK ; TKKGELSIIP ; 250: YEITLLSPCL ; HMLPHLHFGL ; KDKETRYRQR ; YLDLILNDFV ; RQKFIIRSKI ; 300: ITYIRSFLDE ; LGFLEIETPM ; MNIIPGGAVA ; KPFITYHNEL ; DMNLYMRIAP ; 350: ELYHKMLVVG ; GIDRVYEIGR ; QFRNEGIDLT ; HNPEFTTCEF ; YMAYADYHDL ; 400: MEITEKMVSG ; MVKHITGSYK ; VTYHPDGPEG ; QAYDVDFTPP ; FRRINMVEEL ; 450: EKALGMKLPE ; TNLFETEETR ; KILDDICVAK ; AVECPPPRTT ; ARLLDKLVGE ; 500: FLEVTCINPT ; FICDHPQIMS ; PLAKWHRSKE ; GLTERFELFV ; MKKEICNAYT ; 550: ELNDPMRQRQ ; LFEEQAKAKA ; AGDDEAMFID ; ENFCTALEYG ; LPPTAGWGMG ; 597: IDRVAMFLTD ; SNNIKEVLLF ; PAMKPEDKKE ; NVATTDTLES ; TTVGTSV
Sequence Length	597
String	Q15046
Sub Unit	Homodimer; also part of a multisubunit complex that groups AIMP1, AIMP2, EEF1A1 and tRNA ligases for Arg, Asp, Glu, Gln, Ile, Leu, Lys, Met and Pro. Interacts with AIMP2 (via N-terminus) and MITF. Interacts directly with HIV-1 virus GAG protein.

Uniprot	Q15046
Gene Name	KARS
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:3735
Unigene	Hs.3100

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SKU	Supplier No.	Size	Your price	Quantity
BHE13812246	E0187h	96T	$736		Add to Cart

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