JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Human Low-density lipoprotein receptor-related protein 8

SKU : BHE13806114

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E10006h
Alternative Names	Apolipoprotein E receptor 2 ; APOER2
Categories	Elisa
Function	Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. LRP8 has higher affinity for Reelin than VLDLR. LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development. Binds the endoplasmic reticulum resident receptor-associated protein (RAP). Binds dimers of beta 2-glycoprotein I and may be involved in the suppression of platelet aggregation in the vasculature. Highly expressed in the initial segment of the epididymis, where it affects the functional expression of clusterin and phospholipid hydroperoxide glutathione peroxidase (PHGPx), two proteins required for sperm maturation. May also function as an endocytic receptor.
Specificity	Natural and recombinant Human Low-density lipoprotein receptor-related protein 8
Subcellular Location	Cell membrane Single-pass type I membrane protein Secreted Isoforms that contain the exon coding for a furin-type cleavage site are proteolytically processed, leading to a secreted receptor fragment.
Detection Range	0.312-20ng/mL
Entryname	LRP8_HUMAN
Method Type	Sandwich
Platform	PF00057
Protein Name	Low-density lipoprotein receptor-related protein 8
Sensitivity	0.1ng/mL
Sequence	50: MGLPEPGPLR ; LLALLLLLLL ; LLLLQLQHLA ; AAAADPLLGG ; QGPAKDCEKD ; 100: QFQCRNERCI ; PSVWRCDEDD ; DCLDHSDEDD ; CPKKTCADSD ; FTCDNGHCIH ; 150: ERWKCDGEEE ; CPDGSDESEA ; TCTKQVCPAE ; KLSCGPTSHK ; CVPASWRCDG ; 200: EKDCEGGADE ; AGCATLCAPH ; EFQCGNRSCL ; AAVFVCDGDD ; DCGDGSDERG ; 250: CADPACGPRE ; FRCGGDGGGA ; CIPERWVCDR ; QFDCEDRSDE ; AAELCGRPGP ; 300: GATSAPAACA ; TASQFACRSG ; ECVHLGWRCD ; GDRDCKDKSD ; EADCPLGTCR ; 350: GDEFQCGDGT ; CVLAIKHCNQ ; EQDCPDGSDE ; AGCLQGLNEC ; LHNNGGCSHI ; 400: CTDLKIGFEC ; TCPAGFQLLD ; QKTCGDIDEC ; KDPDACSQIC ; VNYKGYFKCE ; 450: CYPGYEMDLL ; TKNCKAAAGK ; SPSLIFTNRH ; EVRRIDLVKR ; NYSRLIPMLK ; 500: NVVALDVEVA ; TNRIYWCDLS ; YRKIYSAYMD ; KASDPKEQEV ; LIDEQLHSPE ; 550: GLAVDWVHKH ; IYWTDSGNKT ; ISVATVDGGR ; RRTLFSRNLS ; EPRAIAVDPL ; 600: RGFMYWSDWG ; DQAKIEKSGL ; NGVDRQTLVS ; DNIEWPNGIT ; LDLLSQRLYW ; 650: VDSKLHQLSS ; IDFSGGNRKT ; LISSTDFLSH ; PFGIAVFEDK ; VFWTDLENEA ; 700: IFSANRLNGL ; EISILAENLN ; NPHDIVIFHE ; LKQPRAPDAC ; ELSVQPNGGC ; 750: EYLCLPAPQI ; SSHSPKYTCA ; CPDTMWLGPD ; MKRCYRAPQS ; TSTTTLASTM ; 800: TRTVPATTRA ; PGTTVHRSTY ; QNHSTETPSL ; TAAVPSSVSV ; PRAPSISPST ; 850: LSPATSNHSQ ; HYANEDSKMG ; STVTAAVIGI ; IVPIVVIALL ; CMSGYLIWRN ; 900: WKRKNTKSMN ; FDNPVYRKTT ; EEEDEDELHI ; GRTAQIGHVY ; PAAISSFDRP ; 950: LWAEPCLGET ; REPEDPAPAL ; KELFVLPGEP ; RSQLHQLPKN ; PLSELPVVKS ; 963: KRVALSLEDD ; GLP
Sequence Length	963
String	Q14114
Sub Unit	Reelin associates with two or more receptor molecules. Interacts with DAB1 and JNK-interacting proteins. Interacts with SNX17.

Uniprot	Q14114
Gene Name	LRP8
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:7804
Unigene	Hs.726256

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13806114	E10006h	96T	$736		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.