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ELISA Kit for Human Low-density lipoprotein receptor-related protein 1B

SKU : BHE13812186

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E10009h
Alternative Names	Low-density lipoprotein receptor-related protein-deleted in tumor ; LRP-DIT ; LRPDIT
Categories	Elisa
Function	Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis.
Specificity	Natural and recombinant Human Low-density lipoprotein receptor-related protein 1B
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	0.625-40ng/mL
Entryname	LRP1B_HUMAN
Method Type	Sandwich
Platform	PF00008
Protein Name	Low-density lipoprotein receptor-related protein 1B
Sensitivity	0.268 ng/mL
Sequence	50: MSEFLLALLT ; LSGLLPIARV ; LTVGADRDQQ ; LCDPGEFLCH ; DHVTCVSQSW ; 100: LCDGDPDCPD ; DSDESLDTCP ; EEVEIKCPLN ; HIACLGTNKC ; VHLSQLCNGV ; 150: LDCPDGYDEG ; VHCQELLSNC ; QQLNCQYKCT ; MVRNSTRCYC ; EDGFEITEDG ; 200: RSCKDQDECA ; VYGTCSQTCR ; NTHGSYTCSC ; VEGYLMQPDN ; RSCKAKIEPT ; 250: DRPPILLIAN ; FETIEVFYLN ; GSKMATLSSV ; NGNEIHTLDF ; IYNEDMICWI ; 300: ESRESSNQLK ; CIQITKAGGL ; TDEWTINILQ ; SFHNVQQMAI ; DWLTRNLYFV ; 350: DHVGDRIFVC ; NSNGSVCVTL ; IDLELHNPKA ; IAVDPIAGKL ; FFTDYGNVAK ; 400: VERCDMDGMN ; RTRIIDSKTE ; QPAALALDLV ; NKLVYWVDLY ; LDYVGVVDYQ ; 450: GKNRHTVIQG ; RQVRHLYGIT ; VFEDYLYATN ; SDNYNIVRIN ; RFNGTDIHSL ; 500: IKIENAWGIR ; IYQKRTQPTV ; RSHACEVDPY ; GMPGGCSHIC ; LLSSSYKTRT ; 550: CRCRTGFNLG ; SDGRSCKRPK ; NELFLFYGKG ; RPGIVRGMDL ; NTKIADEYMI ; 600: PIENLVNPRA ; LDFHAETNYI ; YFADTTSFLI ; GRQKIDGTER ; ETILKDDLDN ; 650: VEGIAVDWIG ; NNLYWTNDGH ; RKTINVARLE ; KASQSRKTLL ; EGEMSHPRGI ; 700: VVDPVNGWMY ; WTDWEEDEID ; DSVGRIEKAW ; MDGFNRQIFV ; TSKMLWPNGL ; 750: TLDFHTNTLY ; WCDAYYDHIE ; KVFLNGTHRK ; IVYSGRELNH ; PFGLSHHGNY ; 800: VFWTDYMNGS ; IFQLDLITSE ; VTLLRHERPP ; LFGLQIYDPR ; KQQGDNMCRV ; 850: NNGGCSTLCL ; AIPGGRVCAC ; ADNQLLDENG ; TTCTFNPGEA ; LPHICKAGEF ; 900: RCKNRHCIQA ; RWKCDGDDDC ; LDGSDEDSVN ; CFNHSCPDDQ ; FKCQNNRCIP ; 950: KRWLCDGAND ; CGSNEDESNQ ; TCTARTCQVD ; QFSCGNGRCI ; PRAWLCDRED ; 1000: DCGDQTDEMA ; SCEFPTCEPL ; TQFVCKSGRC ; ISSKWHCDSD ; DDCGDGSDEV ; 1050: GCVHSCFDNQ ; FRCSSGRCIP ; GHWACDGDND ; CGDFSDEAQI ; NCTKEEIHSP ; 1100: AGCNGNEFQC ; HPDGNCVPDL ; WRCDGEKDCE ; DGSDEKGCNG ; TIRLCDHKTK ; 1150: FSCWSTGRCI ; NKAWVCDGDI ; DCEDQSDEDD ; CDSFLCGPPK ; HPCANDTSVC ; 1200: LQPEKLCNGK ; KDCPDGSDEG ; YLCDECSLNN ; GGCSNHCSVV ; PGRGIVCSCP ; 1250: EGLQLNKDNK ; TCEIVDYCSN ; HLKCSQVCEQ ; HKHTVKCSCY ; EGWKLDVDGE ; 1300: SCTSVDPFEA ; FIIFSIRHEI ; RRIDLHKRDY ; SLLVPGLRNT ; IALDFHFNQS ; 1350: LLYWTDVVED ; RIYRGKLSES ; GGVSAIEVVV ; EHGLATPEGL ; TVDWIAGNIY ; 1400: WIDSNLDQIE ; VAKLDGSLRT ; TLIAGAMEHP ; RAIALDPRYG ; ILFWTDWDAN ; 1450: FPRIESASMS ; GAGRKTIYKD ; MKTGAWPNGL ; TVDHFEKRIV ; WTDARSDAIY ; 1500: SALYDGTNMI ; EIIRGHEYLS ; HPFAVSLYGS ; EVYWTDWRTN ; TLSKANKWTG ; 1550: QNVSVIQKTS ; AQPFDLQIYH ; PSRQPQAPNP ; CAANDGKGPC ; SHMCLINHNR ; 1600: SAACACPHLM ; KLSSDKKTCY ; EMKKFLLYAR ; RSEIRGVDID ; NPYFNFITAF ; 1650: TVPDIDDVTV ; IDFDASEERL ; YWTDIKTQTI ; KRAFINGTGL ; ETVISRDIQS ; 1700: IRGLAVDWVS ; RNLYWISSEF ; DETQINVARL ; DGSLKTSIIH ; GIDKPQCLAA ; 1750: HPVRGKLYWT ; DGNTINMANM ; DGSNSKILFQ ; NQKEPVGLSI ; DYVENKLYWI ; 1800: SSGNGTINRC ; NLDGGNLEVI ; ESMKEELTKA ; TALTIMDKKL ; WWADQNLAQL ; 1850: GTCSKRDGRN ; PTILRNKTSG ; VVHMKVYDKE ; AQQGSNSCQL ; NNGGCSQLCL ; 1900: PTSETTRTCM ; CTVGYYLQKN ; RMSCQGIESF ; LMYSVHEGIR ; GIPLEPSDKM ; 1950: DALMPISGTS ; FAVGIDFHAE ; NDTIYWTDMG ; FNKISRAKRD ; QTWKEDIITN ; 2000: GLGRVEGIAV ; DWIAGNIYWT ; DHGFNLIEVA ; RLNGSFRYVI ; ISQGLDQPRS ; 2050: IAVHPEKGLL ; FWTEWGQMPC ; IGKARLDGSE ; KVVLVSMGIA ; WPNGISIDYE ; 2100: ENKLYWCDAR ; TDKIERIDLE ; TGGNREMVLS ; GSNVDMFSVA ; VFGAYIYWSD ; 2150: RAHANGSVRR ; GHKNDATETI ; TMRTGLGVNL ; KEVKIFNRVR ; EKGTNVCARD ; 2200: NGGCKQLCLY ; RGNSRRTCAC ; AHGYLAEDGV ; TCLRHEGYLL ; YSGRTILKSI ; 2250: HLSDETNLNS ; PIRPYENPRY ; FKNVIALAFD ; YNQRRKGTNR ; IFYSDAHFGN ; 2300: IQLIKDNWED ; RQVIVENVGS ; VEGLAYHRAW ; DTLYWTSSTT ; SSITRHTVDQ ; 2350: TRPGAFDREA ; VITMSEDDHP ; HVLALDECQN ; LMFWTNWNEQ ; HPSIMRSTLT ; 2400: GKNAQVVVST ; DILTPNGLTI ; DYRAEKLYFS ; DGSLGKIERC ; EYDGSQRHVI ; 2450: VKSGPGTFLS ; LAVYDNYIFW ; SDWGRRAILR ; SNKYTGGDTK ; ILRSDIPHQP ; 2500: MGIIAVANDT ; NSCELSPCAL ; LNGGCHDLCL ; LTPNGRVNCS ; CRGDRILLED ; 2550: NRCVTKNSSC ; NAYSEFECGN ; GECIDYQLTC ; DGIPHCKDKS ; DEKLLYCENR ; 2600: SCRRGFKPCY ; NRRCIPHGKL ; CDGENDCGDN ; SDELDCKVST ; CATVEFRCAD ; 2650: GTCIPRSARC ; NQNIDCADAS ; DEKNCNNTDC ; THFYKLGVKT ; TGFIRCNSTS ; 2700: LCVLPTWICD ; GSNDCGDYSD ; ELKCPVQNKH ; KCEENYFSCP ; SGRCILNTWI ; 2750: CDGQKDCEDG ; RDEFHCDSSC ; SWNQFACSAQ ; KCISKHWICD ; GEDDCGDGLD ; 2800: ESDSICGAIT ; CAADMFSCQG ; SRACVPRHWL ; CDGERDCPDG ; SDELSTAGCA ; 2850: PNNTCDENAF ; MCHNKVCIPK ; QFVCDHDDDC ; GDGSDESPQC ; GYRQCGTEEF ; 2900: SCADGRCLLN ; TQWQCDGDFD ; CPDHSDEAPL ; NPKCKSAEQS ; CNSSFFMCKN ; 2950: GRCIPSGGLC ; DNKDDCGDGS ; DERNCHINEC ; LSKKVSGCSQ ; DCQDLPVSYK ; 3000: CKCWPGFQLK ; DDGKTCVDID ; ECSSGFPCSQ ; QCINTYGTYK ; CLCTDGYEIQ ; 3050: PDNPNGCKSL ; SDEEPFLILA ; DHHEIRKIST ; DGSNYTLLKQ ; GLNNVIAIDF ; 3100: DYREEFIYWI ; DSSRPNGSRI ; NRMCLNGSDI ; KVVHNTAVPN ; ALAVDWIGKN ; 3150: LYWSDTEKRI ; IEVSKLNGLY ; PTILVSKRLK ; FPRDLSLDPQ ; AGYLYWIDCC ; 3200: EYPHIGRVGM ; DGTNQSVVIE ; TKISRPMALT ; IDYVNRRLYW ; ADENHIEFSN ; 3250: MDGSHRHKVP ; NQDIPGVIAL ; TLFEDYIYWT ; DGKTKSLSRA ; HKTSGADRLS ; 3300: LIYSWHAITD ; IQVYHSYRQP ; DVSKHLCMIN ; NGGCSHLCLL ; APGKTHTCAC ; 3350: PTNFYLAADN ; RTCLSNCTAS ; QFRCKTDKCI ; PFWWKCDTVD ; DCGDGSDEPD ; 3400: DCPEFRCQPG ; RFQCGTGLCA ; LPAFICDGEN ; DCGDNSDELN ; CDTHVCLSGQ ; 3450: FKCTKNQKCI ; PVNLRCNGQD ; DCGDEEDERD ; CPENSCSPDY ; FQCKTTKHCI ; 3500: SKLWVCDEDP ; DCADASDEAN ; CDKKTCGPHE ; FQCKNNNCIP ; DHWRCDSQND ; 3550: CSDNSDEENC ; KPQTCTLKDF ; LCANGDCVSS ; RFWCDGDFDC ; ADGSDERNCE ; 3600: TSCSKDQFRC ; SNGQCIPAKW ; KCDGHEDCKY ; GEDEKSCEPA ; SPTCSSREYI ; 3650: CASDGCISAS ; LKCNGEYDCA ; DGSDEMDCVT ; ECKEDQFRCK ; NKAHCIPIRW ; 3700: LCDGIHDCVD ; GSDEENCERG ; GNICRADEFL ; CNNSLCKLHF ; WVCDGEDDCG ; 3750: DNSDEAPDMC ; VKFLCPSTRP ; HRCRNNRICL ; QSEQMCNGID ; ECGDNSDEDH ; 3800: CGGKLTYKAR ; PCKKDEFACS ; NKKCIPMDLQ ; CDRLDDCGDG ; SDEQGCRIAP ; 3850: TEYTCEDNVN ; PCGDDAYCNQ ; IKTSVFCRCK ; PGFQRNMKNR ; QCEDLNECLV ; 3900: FGTCSHQCIN ; VEGSYKCVCD ; QNFQERNNTC ; IAEGSEDQVL ; YIANDTDILG ; 3950: FIYPFNYSGD ; HQQISHIEHN ; SRITGMDVYY ; QRDMIIWSTQ ; FNPGGIFYKR ; 4000: IHGREKRQAN ; SGLICPEFKR ; PRDIAVDWVA ; GNIYWTDHSR ; MHWFSYYTTH ; 4050: WTSLRYSINV ; GQLNGPNCTR ; LLTNMAGEPY ; AIAVNPKRGM ; MYWTVVGDHS ; 4100: HIEEAAMDGT ; LRRILVQKNL ; QRPTGLAVDY ; FSERIYWADF ; ELSIIGSVLY ; 4150: DGSNSVVSVS ; SKQGLLHPHR ; IDIFEDYIYG ; AGPKNGVFRV ; QKFGHGSVEY ; 4200: LALNIDKTKG ; VLISHRYKQL ; DLPNPCLDLA ; CEFLCLLNPS ; GATCVCPEGK ; 4250: YLINGTCNDD ; SLLDDSCKLT ; CENGGRCILN ; EKGDLRCHCW ; PSYSGERCEV ; 4300: NHCSNYCQNG ; GTCVPSVLGR ; PTCSCALGFT ; GPNCGKTVCE ; DFCQNGGTCI ; 4350: VTAGNQPYCH ; CQPEYTGDRC ; QYYVCHHYCV ; NSESCTIGDD ; GSVECVCPTR ; 4400: YEGPKCEVDK ; CVRCHGGHCI ; INKDSEDIFC ; NCTNGKIASS ; CQLCDGYCYN ; 4450: GGTCQLDPET ; NVPVCLCSTN ; WSGTQCERPA ; PKSSKSDHIS ; TRSIAIIVPL ; 4500: VLLVTLITTL ; VIGLVLCKRK ; RRTKTIRRQP ; IINGGINVEI ; GNPSYNMYEV ; 4550: DHDHNDGGLL ; DPGFMIDPTK ; ARYIGGGPSA ; FKLPHTAPPI ; YLNSDLKGPL ; 4599: TAGPTNYSNP ; VYAKLYMDGQ ; NCRNSLGSVD ; ERKELLPKKI ; EIGIRETVA
Sequence Length	4599
String	Q9NZR2
Sub Unit	Binds LRPAP1, PLAU, PLAT and SERPINE1; binding is followed by internalization and degradation of the ligands.

Uniprot	Q9NZR2
Gene Name	LRP1B
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:53353
Unigene	Hs.656461

Reference	1. "LRP-DIT, a putative endocytic receptor gene, is frequently inactivated in non-small cell lung cancer cell lines." Liu C.-X., Musco S., Lisitsina N.M., Forgacs E., Minna J.D., Lisitsyn N.A. Cancer Res.60:1961-1967(2000) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT CYS-3157 tissue: Lung cancer. 2. "Genomic organization of a new candidate tumor suppressor gene, LRP1B." Liu C.-X., Musco S., Lisitsina N.M., Yaklichkin S.Y., Lisitsyn N.A. Genomics69:271-274(2000) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-2655 AND 2677-4213 3. "The putative tumor suppressor LRP1B, a novel member of the low density lipoprotein (LDL) receptor family, exhibits both overlapping and distinct properties with the LDL receptor-related protein." Liu C.-X., Li Y., Obermoeller-McCormick L.M., Schwartz A.L., Bu G. J. Biol. Chem.276:28889-28896(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH LRPAP1; PLAU; PLAT AND SERPINE1;TISSUE SPECIFICITY

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