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ELISA Kit for Human Leucine-rich PPR motif-containing protein, mitochondrial

SKU : BHE13806779

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E14393h
Alternative Names	130 kDa leucine-rich protein ; LRP 130 ; GP130 ; LRP130
Categories	Elisa
Function	May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA.
Specificity	Natural and recombinant Human Leucine-rich PPR motif-containing protein, mitochondrial
Subcellular Location	Mitochondrion Nucleus nucleoplasm Nucleus inner membrane Nucleus outer membrane Seems to be predominantly mitochondrial.
Detection Range	78-5000pg/ml
Entryname	LPPRC_HUMAN
Method Type	Sandwich
Platform	PF01535
Protein Name	Leucine-rich PPR motif-containing protein, mitochondrial
Sensitivity	39.03pg/mL
Sequence	50: MAALLRSARW ; LLRAGAAPRL ; PLSLRLLPGG ; PGRLHAASYL ; PAARAGPVAG ; 100: GLLSPARLYA ; IAAKEKDIQE ; ESTFSSRKIS ; NQFDWALMRL ; DLSVRRTGRI ; 150: PKKLLQKVFN ; DTCRSGGLGG ; SHALLLLRSC ; GSLLPELKLE ; ERTEFAHRIW ; 200: DTLQKLGAVY ; DVSHYNALLK ; VYLQNEYKFS ; PTDFLAKMEE ; ANIQPNRVTY ; 250: QRLIASYCNV ; GDIEGASKIL ; GFMKTKDLPV ; TEAVFSALVT ; GHARAGDMEN ; 300: AENILTVMRD ; AGIEPGPDTY ; LALLNAYAEK ; GDIDHVKQTL ; EKVEKSELHL ; 350: MDRDLLQIIF ; SFSKAGYPQY ; VSEILEKVTC ; ERRYIPDAMN ; LILLLVTEKL ; 400: EDVALQILLA ; CPVSKEDGPS ; VFGSFFLQHC ; VTMNTPVEKL ; TDYCKKLKEV ; 450: QMHSFPLQFT ; LHCALLANKT ; DLAKALMKAV ; KEEGFPIRPH ; YFWPLLVGRR ; 500: KEKNVQGIIE ; ILKGMQELGV ; HPDQETYTDY ; VIPCFDSVNS ; ARAILQENGC ; 550: LSDSDMFSQA ; GLRSEAANGN ; LDFVLSFLKS ; NTLPISLQSI ; RSSLLLGFRR ; 600: SMNINLWSEI ; TELLYKDGRY ; CQEPRGPTEA ; VGYFLYNLID ; SMSDSEVQAK ; 650: EEHLRQYFHQ ; LEKMNVKIPE ; NIYRGIRNLL ; ESYHVPELIK ; DAHLLVESKN ; 700: LDFQKTVQLT ; SSELESTLET ; LKAENQPIRD ; VLKQLILVLC ; SEENMQKALE ; 750: LKAKYESDMV ; TGGYAALINL ; CCRHDKVEDA ; LNLKEEFDRL ; DSSAVLDTGK ; 800: YVGLVRVLAK ; HGKLQDAINI ; LKEMKEKDVL ; IKDTTALSFF ; HMLNGAALRG ; 850: EIETVKQLHE ; AIVTLGLAEP ; STNISFPLVT ; VHLEKGDLST ; ALEVAIDCYE ; 900: KYKVLPRIHD ; VLCKLVEKGE ; TDLIQKAMDF ; VSQEQGEMVM ; LYDLFFAFLQ ; 950: TGNYKEAKKI ; IETPGIRARS ; ARLQWFCDRC ; VANNQVETLE ; KLVELTQKLF ; 1000: ECDRDQMYYN ; LLKLYKINGD ; WQRADAVWNK ; IQEENVIPRE ; KTLRLLAEIL ; 1050: REGNQEVPFD ; VPELWYEDEK ; HSLNSSSAST ; TEPDFQKDIL ; IACRLNQKKG ; 1100: AYDIFLNAKE ; QNIVFNAETY ; SNLIKLLMSE ; DYFTQAMEVK ; AFAETHIKGF ; 1150: TLNDAANSRL ; IITQVRRDYL ; KEAVTTLKTV ; LDQQQTPSRL ; AVTRVIQALA ; 1200: MKGDVENIEV ; VQKMLNGLED ; SIGLSKMVFI ; NNIALAQIKN ; NNIDAAIENI ; 1250: ENMLTSENKV ; IEPQYFGLAY ; LFRKVIEEQL ; EPAVEKISIM ; AERLANQFAI ; 1300: YKPVTDFFLQ ; LVDAGKVDDA ; RALLQRCGAI ; AEQTPILLLF ; LLRNSRKQGK ; 1350: ASTVKSVLEL ; IPELNEKEEA ; YNSLMKSYVS ; EKDVTSAKAL ; YEHLTAKNTK ; 1394: LDDLFLKRYA ; SLLKYAGEPV ; PFIEPPESFE ; FYAQQLRKLR ; ENSS
Sequence Length	1394
String	P42704
Sub Unit	Interacts with CECR2, HEBP2, MAP1S and UXT. Interacts with PPARGC1A. Interacts with FOXO1 (By similarity). Component of mRNP complexes associated with HNRPA1.

Uniprot	P42704
Gene Name	LRPPRC
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:10128
Unigene	Hs.368084

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806779	E14393h	96T	$736		Add to Cart

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