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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Iron-responsive element-binding protein 2

SKU : BHE13806057

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E13568h
Alternative Names	Iron regulatory protein 2 ; IRP2
Categories	Elisa
Function	RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
Specificity	Natural and recombinant Human Iron-responsive element-binding protein 2
Subcellular Location	Cytoplasm
Detection Range	0.312-20ng/mL
Entryname	IREB2_HUMAN
Method Type	Sandwich
Platform	PF00330
Protein Name	Iron-responsive element-binding protein 2
Sensitivity	0.098ng/ml
Sequence	50: MDAPKAGYAF ; EYLIETLNDS ; SHKKFFDVSK ; LGTKYDVLPY ; SIRVLLEAAV ; 100: RNCDGFLMKK ; EDVMNILDWK ; TKQSNVEVPF ; FPARVLLQDF ; TGIPAMVDFA ; 150: AMREAVKTLG ; GDPEKVHPAC ; PTDLTVDHSL ; QIDFSKCAIQ ; NAPNPGGGDL ; 200: QKAGKLSPVK ; VQPKKLPCRG ; QTTCRGSCDS ; GELGRNSGTF ; SSQIENTPIL ; 250: CPFHLQPVPE ; PETVLKNQEV ; EFGRNRERLQ ; FFKWSSRVFK ; NVAVIPPGTG ; 300: MAHQINLEYL ; SRVVFEEKDL ; LFPDSVVGTD ; SHITMVNGLG ; ILGWGVGGIE ; 350: TEAVMLGLPV ; SLTLPEVVGC ; ELTGSSNPFV ; TSIDVVLGIT ; KHLRQVGVAG ; 400: KFVEFFGSGV ; SQLSIVDRTT ; IANMCPEYGA ; ILSFFPVDNV ; TLKHLEHTGF ; 450: SKAKLESMET ; YLKAVKLFRN ; DQNSSGEPEY ; SQVIQINLNS ; IVPSVSGPKR ; 500: PQDRVAVTDM ; KSDFQACLNE ; KVGFKGFQIA ; AEKQKDIVSI ; HYEGSEYKLS ; 550: HGSVVIAAVI ; SCTNNCNPSV ; MLAAGLLAKK ; AVEAGLRVKP ; YIRTSLSPGS ; 600: GMVTHYLSSS ; GVLPYLSKLG ; FEIVGYGCSI ; CVGNTAPLSD ; AVLNAVKQGD ; 650: LVTCGILSGN ; KNFEGRLCDC ; VRANYLASPP ; LVVAYAIAGT ; VNIDFQTEPL ; 700: GTDPTGKNIY ; LHDIWPSREE ; VHRVEEEHVI ; LSMFKALKDK ; IEMGNKRWNS ; 750: LEAPDSVLFP ; WDLKSTYIRC ; PSFFDKLTKE ; PIALQAIENA ; HVLLYLGDSV ; 800: TTDHISPAGS ; IARNSAAAKY ; LTNRGLTPRE ; FNSYGARRGN ; DAVMTRGTFA ; 850: NIKLFNKFIG ; KPAPKTIHFP ; SGQTLDVFEA ; AELYQKEGIP ; LIILAGKKYG ; 900: SGNSRDWAAK ; GPYLLGVKAV ; LAESYEKIHK ; DHLIGIGIAP ; LQFLPGENAD ; 950: SLGLSGRETF ; SLTFPEELSP ; GITLNIQTST ; GKVFSVIASF ; EDDVEITLYK ; 963: HGGLLNFVAR ; KFS
Sequence Length	963
String	P48200
Sub Unit	Interacts with RBCK1 isoform 1 and isoform 2 only in iron-rich conditions. Interacts (when associated with the 4Fe-4S) with FBXL5.

Uniprot	P48200
Gene Name	IREB2
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:3658
Unigene	Hs.436031

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806057	E13568h	96T	$736		Add to Cart

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