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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Integrin alpha-4

SKU : BHE13805887

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1511h
Alternative Names	CD49 antigen-like family member D ; Integrin alpha-IV ; VLA-4 subunit alpha ; CD49d ; CD49D
Categories	Elisa
Function	Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.
Specificity	Natural and recombinant Human Integrin alpha-4
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	0.156-10ng/mL
Entryname	ITA4_HUMAN
Method Type	Sandwich
Platform	PF01839
Protein Name	Integrin alpha-4
Sensitivity	0.078ng/mL
Sequence	50: MAWEARREPG ; PRRAAVRETV ; MLLLCLGVPT ; GRPYNVDTES ; ALLYQGPHNT ; 100: LFGYSVVLHS ; HGANRWLLVG ; APTANWLANA ; SVINPGAIYR ; CRIGKNPGQT ; 150: CEQLQLGSPN ; GEPCGKTCLE ; ERDNQWLGVT ; LSRQPGENGS ; IVTCGHRWKN ; 200: IFYIKNENKL ; PTGGCYGVPP ; DLRTELSKRI ; APCYQDYVKK ; FGENFASCQA ; 250: GISSFYTKDL ; IVMGAPGSSY ; WTGSLFVYNI ; TTNKYKAFLD ; KQNQVKFGSY ; 300: LGYSVGAGHF ; RSQHTTEVVG ; GAPQHEQIGK ; AYIFSIDEKE ; LNILHEMKGK ; 350: KLGSYFGASV ; CAVDLNADGF ; SDLLVGAPMQ ; STIREEGRVF ; VYINSGSGAV ; 400: MNAMETNLVG ; SDKYAARFGE ; SIVNLGDIDN ; DGFEDVAIGA ; PQEDDLQGAI ; 450: YIYNGRADGI ; SSTFSQRIEG ; LQISKSLSMF ; GQSISGQIDA ; DNNGYVDVAV ; 500: GAFRSDSAVL ; LRTRPVVIVD ; ASLSHPESVN ; RTKFDCVENG ; WPSVCIDLTL ; 550: CFSYKGKEVP ; GYIVLFYNMS ; LDVNRKAESP ; PRFYFSSNGT ; SDVITGSIQV ; 600: SSREANCRTH ; QAFMRKDVRD ; ILTPIQIEAA ; YHLGPHVISK ; RSTEEFPPLQ ; 650: PILQQKKEKD ; IMKKTINFAR ; FCAHENCSAD ; LQVSAKIGFL ; KPHENKTYLA ; 700: VGSMKTLMLN ; VSLFNAGDDA ; YETTLHVKLP ; VGLYFIKILE ; LEEKQINCEV ; 750: TDNSGVVQLD ; CSIGYIYVDH ; LSRIDISFLL ; DVSSLSRAEE ; DLSITVHATC ; 800: ENEEEMDNLK ; HSRVTVAIPL ; KYEVKLTVHG ; FVNPTSFVYG ; SNDENEPETC ; 850: MVEKMNLTFH ; VINTGNSMAP ; NVSVEIMVPN ; SFSPQTDKLF ; NILDVQTTTG ; 900: ECHFENYQRV ; CALEQQKSAM ; QTLKGIVRFL ; SKTDKRLLYC ; IKADPHCLNF ; 950: LCNFGKMESG ; KEASVHIQLE ; GRPSILEMDE ; TSALKFEIRA ; TGFPEPNPRV ; 1000: IELNKDENVA ; HVLLEGLHHQ ; RPKRYFTIVI ; ISSSLLLGLI ; VLLLISYVMW ; 1032: KAGFFKRQYK ; SILQEENRRD ; SWSYINSKSN ; DD
Sequence Length	1032
String	P13612
Sub Unit	Heterodimer of an alpha and a beta subunit. The alpha subunit can sometimes be cleaved into two non-covalently associated fragments. Alpha-4 associates with either beta-1 or beta-7. Alpha-4 interacts with PXN, LPXN, and TGFB1I1/HIC5. Interacts with CSPG4 through CSPG4 chondroitin sulfate glycosaminoglycan.

Uniprot	P13612
Gene Name	ITGA4
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:3676
Unigene	Hs.440955

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805887	E1511h	96T	$736		Add to Cart

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