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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Insulin-degrading enzyme

SKU : BHE13805374

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1897h
Alternative Names	Abeta-degrading protease ; Insulin protease ; Insulinase ; Insulysin
Categories	Elisa
Function	Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.
Specificity	Natural and recombinant Human Insulin-degrading enzyme
Subcellular Location	Cytoplasm Cell surface Present at the cell surface of neuron cells. The membrane-associated isoform is approximately 5 kDa larger than the known cytosolic isoform.
Detection Range	0.156-10ng/mL
Entryname	IDE_HUMAN
Method Type	Sandwich
Platform	PF00675
Protein Name	Insulin-degrading enzyme
Sensitivity	0.078ng/mL
Sequence	50: MRYRLAWLLH ; PALPSTFRSV ; LGARLPPPER ; LCGFQKKTYS ; KMNNPAIKRI ; 100: GNHITKSPED ; KREYRGLELA ; NGIKVLLISD ; PTTDKSSAAL ; DVHIGSLSDP ; 150: PNIAGLSHFC ; EHMLFLGTKK ; YPKENEYSQF ; LSEHAGSSNA ; FTSGEHTNYY ; 200: FDVSHEHLEG ; ALDRFAQFFL ; CPLFDESCKD ; REVNAVDSEH ; EKNVMNDAWR ; 250: LFQLEKATGN ; PKHPFSKFGT ; GNKYTLETRP ; NQEGIDVRQE ; LLKFHSAYYS ; 300: SNLMAVCVLG ; RESLDDLTNL ; VVKLFSEVEN ; KNVPLPEFPE ; HPFQEEHLKQ ; 350: LYKIVPIKDI ; RNLYVTFPIP ; DLQKYYKSNP ; GHYLGHLIGH ; EGPGSLLSEL ; 400: KSKGWVNTLV ; GGQKEGARGF ; MFFIINVDLT ; EEGLLHVEDI ; ILHMFQYIQK ; 450: LRAEGPQEWV ; FQECKDLNAV ; AFRFKDKERP ; RGYTSKIAGI ; LHYYPLEEVL ; 500: TAEYLLEEFR ; PDLIEMVLDK ; LRPENVRVAI ; VSKSFEGKTD ; RTEEWYGTQY ; 550: KQEAIPDEVI ; KKWQNADLNG ; KFKLPTKNEF ; IPTNFEILPL ; EKEATPYPAL ; 600: IKDTAMSKLW ; FKQDDKFFLP ; KACLNFEFFS ; PFAYVDPLHC ; NMAYLYLELL ; 650: KDSLNEYAYA ; AELAGLSYDL ; QNTIYGMYLS ; VKGYNDKQPI ; LLKKIIEKMA ; 700: TFEIDEKRFE ; IIKEAYMRSL ; NNFRAEQPHQ ; HAMYYLRLLM ; TEVAWTKDEL ; 750: KEALDDVTLP ; RLKAFIPQLL ; SRLHIEALLH ; GNITKQAALG ; IMQMVEDTLI ; 800: EHAHTKPLLP ; SQLVRYREVQ ; LPDRGWFVYQ ; QRNEVHNNCG ; IEIYYQTDMQ ; 850: STSENMFLEL ; FCQIISEPCF ; NTLRTKEQLG ; YIVFSGPRRA ; NGIQGLRFII ; 900: QSEKPPHYLE ; SRVEAFLITM ; EKSIEDMTEE ; AFQKHIQALA ; IRRLDKPKKL ; 950: SAECAKYWGE ; IISQQYNFDR ; DNTEVAYLKT ; LTKEDIIKFY ; KEMLAVDAPR ; 1000: RHKVSVHVLA ; REMDSCPVVG ; EFPCQNDINL ; SQAPALPQPE ; VIQNMTEFKR ; 1019: GLPLFPLVKP ; HINFMAAKL
Sequence Length	1019
String	P14735
Sub Unit	Homodimer. Can form higher oligomers. Interacts (via N-terminus) with varicella-zoster virus (VZV) envelope glycoprotein E (via N-terminus); the membrane-associated isoform may function as an entry receptor for this virus.

Uniprot	P14735
Gene Name	IDE
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:3416
Unigene	Hs.500546

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805374	E1897h	96T	$736		Add to Cart

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