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ELISA Kit for Human Inositol monophosphatase 2

SKU : BHE13805811

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0608h
Alternative Names	Inositol-1(or 4)-monophosphatase 2 ; Myo-inositol monophosphatase A2 ; IMP.18P
Categories	Elisa
Function	Can use myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. Has been implicated as the pharmacological target for lithium Li(+) action in brain.
Specificity	Natural and recombinant Human Inositol monophosphatase 2
Detection Range	62.5-4000pg/mL
Entryname	IMPA2_HUMAN
Method Type	Sandwich
Platform	PF00459
Protein Name	Inositol monophosphatase 2
Sensitivity	37pg/mL
Sequence	50: MKPSGEDQAA ; LAAGPWEECF ; QAAVQLALRA ; GQIIRKALTE ; EKRVSTKTSA ; 100: ADLVTETDHL ; VEDLIISELR ; ERFPSHRFIA ; EEAAASGAKC ; VLTHSPTWII ; 150: DPIDGTCNFV ; HRFPTVAVSI ; GFAVRQELEF ; GVIYHCTEER ; LYTGRRGRGA ; 200: FCNGQRLRVS ; GETDLSKALV ; LTEIGPKRDP ; ATLKLFLSNM ; ERLLHAKAHG ; 250: VRVIGSSTLA ; LCHLASGAAD ; AYYQFGLHCW ; DLAAATVIIR ; EAGGIVIDTS ; 288: GGPLDLMACR ; VVAASTREMA ; MLIAQALQTI ; NYGRDDEK
Sequence Length	288
String	O14732
Sub Unit	Homodimer.

Uniprot	O14732
Gene Name	IMPA2
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:3613
Unigene	Hs.743311

Reference	1. "A novel human myo-inositol monophosphatase gene, IMP.18p, maps to a susceptibility region for bipolar disorder." Yoshikawa T., Turner G., Esterling L.E., Sanders A.R., Detera-Wadleigh S.D. Mol. Psychiatry2:393-397(1997) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1) 2. "A human myo-inositol monophosphatase gene (IMPA2) localized in a putative susceptibility region for bipolar disorder on chromosome 18p11.2: genomic structure and polymorphism screening in manic-depressive patients." Sjoeholt G., Gulbrandsen A.K., Lovlie R., Berle J., Molven A., Steen V.M. Mol. Psychiatry5:172-180(2000) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] 3. "Molecular characterization of a novel form of human brain inositol monophosphatase A2b." Parthasarathy L., Parthasarathy R. Submitted (1999-10) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2) 4. "Cloning of human full-length CDSs in BD Creator(TM) system donor vector." Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A. Submitted (2003-05) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1) 5. NHLBI resequencing and genotyping service (RS&G) Submitted (2007-02) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] 6. Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.more... Submitted (2005-09) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1) tissue: Skin. 8. "Lithium modulation of the human inositol monophosphatase 2 (IMPA2) promoter." Seelan R.S., Parthasarathy L.K., Parthasarathy R.N. Biochem. Biophys. Res. Commun.324:1370-1378(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION 9. "Spatial expression patterns and biochemical properties distinguish a second myo-inositol monophosphatase IMPA2 from IMPA1." Ohnishi T., Ohba H., Seo K.-C., Im J., Sato Y., Iwayama Y., Furuichi T., Chung S.-K., Yoshikawa T. J. Biol. Chem.282:637-646(2007) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF ASP-104;ENZYME REGULATION;COFACTOR;BIOPHYSICOCHEMICAL PROPERTIES;HOMODIMERIZATION 10. "Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS] 11. "Crystal structure of human myo-inositol monophosphatase 2, the product of the putative susceptibility gene for bipolar disorder, schizophrenia, and febrile seizures." Arai R., Ito K., Ohnishi T., Ohba H., Akasaka R., Bessho Y., Hanawa-Suetsugu K., Yoshikawa T., Shirouzu M., Yokoyama S. Proteins67:732-742(2007) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS) IN COMPLEX WITH SUBSTRATE;HOMODIMERIZATION 12. "Structure of human inositol monophosphatase 2." Structural genomics consortium (SGC) Submitted (2009-02) to the PDB data bank [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 16-288

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