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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Histone deacetylase 7

SKU : BHE13805341

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E11378h
Alternative Names	Histone deacetylase 7A ; HD7a ; HDAC7A
Categories	Elisa
Function	Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene.
Specificity	Natural and recombinant Human Histone deacetylase 7
Subcellular Location	Nucleus Cytoplasm In the nucleus, it associates with distinct subnuclear dot-like structures. Shuttles between the nucleus and the cytoplasm. Treatment with EDN1 results in shuttling from the nucleus to the perinuclear region. The export to cytoplasm depends on the interaction with the 14-3-3 protein YWHAE and is due to its phosphorylation.
Detection Range	0.312-20ng/mL
Entryname	HDAC7_HUMAN
Method Type	Sandwich
Platform	PF00850
Protein Name	Histone deacetylase 7
Sensitivity	0.1ng/ml
Sequence	50: MDLRVGQRPP ; VEPPPEPTLL ; ALQRPQRLHH ; HLFLAGLQQQ ; RSVEPMRLSM ; 100: DTPMPELQVG ; PQEQELRQLL ; HKDKSKRSAV ; ASSVVKQKLA ; EVILKKQQAA ; 150: LERTVHPNSP ; GIPYRTLEPL ; ETEGATRSML ; SSFLPPVPSL ; PSDPPEHFPL ; 200: RKTVSEPNLK ; LRYKPKKSLE ; RRKNPLLRKE ; SAPPSLRRRP ; AETLGDSSPS ; 250: SSSTPASGCS ; SPNDSEHGPN ; PILGSEALLG ; QRLRLQETSV ; APFALPTVSL ; 300: LPAITLGLPA ; PARADSDRRT ; HPTLGPRGPI ; LGSPHTPLFL ; PHGLEPEAGG ; 350: TLPSRLQPIL ; LLDPSGSHAP ; LLTVPGLGPL ; PFHFAQSLMT ; TERLSGSGLH ; 400: WPLSRTRSEP ; LPPSATAPPP ; PGPMQPRLEQ ; LKTHVQVIKR ; SAKPSEKPRL ; 450: RQIPSAEDLE ; TDGGGPGQVV ; DDGLEHRELG ; HGQPEARGPA ; PLQQHPQVLL ; 500: WEQQRLAGRL ; PRGSTGDTVL ; LPLAQGGHRP ; LSRAQSSPAA ; PASLSAPEPA ; 550: SQARVLSSSE ; TPARTLPFTT ; GLIYDSVMLK ; HQCSCGDNSR ; HPEHAGRIQS ; 600: IWSRLQERGL ; RSQCECLRGR ; KASLEELQSV ; HSERHVLLYG ; TNPLSRLKLD ; 650: NGKLAGLLAQ ; RMFVMLPCGG ; VGVDTDTIWN ; ELHSSNAARW ; AAGSVTDLAF ; 700: KVASRELKNG ; FAVVRPPGHH ; ADHSTAMGFC ; FFNSVAIACR ; QLQQQSKASK ; 750: ILIVDWDVHH ; GNGTQQTFYQ ; DPSVLYISLH ; RHDDGNFFPG ; SGAVDEVGAG ; 800: SGEGFNVNVA ; WAGGLDPPMG ; DPEYLAAFRI ; VVMPIAREFS ; PDLVLVSAGF ; 850: DAAEGHPAPL ; GGYHVSAKCF ; GYMTQQLMNL ; AGGAVVLALE ; GGHDLTAICD ; 900: ASEACVAALL ; GNRVDPLSEE ; GWKQKPNLNA ; IRSLEAVIRV ; HSKYWGCMQR ; 950: LASCPDSWVP ; RVPGADKEEV ; EAVTALASLS ; VGILAEDRPS ; EQLVEEEEPM ; 952: NL
Sequence Length	952
String	Q8WUI4
Sub Unit	Interacts with HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, NCOR1, NCOR2, SIN3A, SIN3B, RBBP4, RBBP7, MTA1L1, SAP30 and MBD3. Interacts with the 14-3-3 protein YWHAE, MEF2A, MEF2B and MEF2C (By similarity). Interacts with KAT5 and EDNRA. Interacts with KDM5B.

Uniprot	Q8WUI4
Gene Name	HDAC7
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:51564
Unigene	Hs.200063

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805341	E11378h	96T	$736		Add to Cart

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